Nature Search

A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Bias-free solar hydrogen production at 19.8 mA cm⁻² using perovskite photocathode and lignocellulosic biomass

While light-driven water splitting offers a means to produce renewable H₂ fuel, water oxidation limits performances and yields low-value products. Here, authors demonstrate a photoelectrochemical cell that converts lignocellulosic biomass into valuable products alongside H₂.

Yuri Choi
Rashmi Mehrotra
Jungki Ryu
ResearchOpen Access03 Oct 2022
Nature Communications

Volume: 13, P: 1-9
Structural basis of organic cation transporter-3 inhibition

The current work reports the structure of the human organic cation transporter 3 (OCT3 / SLC22A3) and provides the structural basis of its inhibition by two specific inhibitors, decynium-22 and corticosterone.

Basavraj Khanppnavar
Julian Maier
Harald H. Sitte
ResearchOpen Access07 Nov 2022
Nature Communications

Volume: 13, P: 1-13
Bias and sensitivity in numerosity perception of negative emotions among individuals with high social anxiety

Jae-Won Yang
Jongsoo Baek
ResearchOpen Access04 Jul 2022
Scientific Reports

Volume: 12, P: 1-8
Changes in retro-odontoid mass after upper cervical spine surgery

Jae-Won Shin
Kyung-Soo Suk
Jane F. Garcia
ResearchOpen Access21 Nov 2022
Scientific Reports

Volume: 12, P: 1-8
Transient fixation of L4 vertebra preserves lumbar motion and function in Lenke Type 5C and 6C scoliosis

Jae-Ho Yang
Jae-Won Shin
Hak-Sun Kim
ResearchOpen Access13 May 2021
Scientific Reports

Volume: 11, P: 1-9
Systematic identification of genomic markers of drug sensitivity in cancer cells

Human cancer cell lines are screened with drugs, undergoing clinical or preclinical investigation, to determine specific genomic alterations associated with response to therapeutic agents.

Mathew J. Garnett
Elena J. Edelman
Cyril H. Benes
Research28 Mar 2012
Nature

Volume: 483, P: 570-575
High-resolution nanotransfer printing applicable to diverse surfaces via interface-targeted adhesion switching

There is an ongoing need for high resolution, versatile and simplistic nanoscale lithography and transfer. Here the authors report a solvent-assisted nanotransfer printing route, which allows for the easy release of 8–20 nm scale features on to a range of substrates.

Jae Won Jeong
Se Ryeun Yang
Yeon Sik Jung
Research10 Nov 2014
Nature Communications

Volume: 5, P: 1-12
Cell membrane cholesterol affects serotonin transporter efflux due to altered transporter oligomerization

Deborah Rudin
Dino Luethi
Harald H. Sitte
ResearchOpen Access02 Sept 2025
Molecular Psychiatry

Volume: 31, P: 963-975
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

A new strategy for derivation of human midbrain dopamine neurons from pluripotent cells was developed; transplantation of the neurons in mice, rats and parkinsonian monkeys show they are a promising source of cells for applications in regenerative medicine.

Sonja Kriks
Jae-Won Shim
Lorenz Studer
Research06 Nov 2011
Nature

Volume: 480, P: 547-551
Novel Therapeutic Effects of Non-thermal atmospheric pressure plasma for Muscle Regeneration and Differentiation

Jae Won Choi
Sung Un Kang
Chul-Ho Kim
ResearchOpen Access28 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
An increase of lysosomes through EGF-triggered endocytosis attenuated zinc-mediated lysosomal membrane permeabilization and neuronal cell death

Jae-Won Eom
Jin-Yeon Lee
Yang-Hee Kim
ResearchOpen Access13 Nov 2024
Cell Death & Disease

Volume: 15, P: 1-16
Interactions of calmodulin kinase II with the dopamine transporter facilitate cocaine-induced enhancement of evoked dopamine release

Jacqueline D. Keighron
Jordi Bonaventura
Gianluigi Tanda
ResearchOpen Access13 Jun 2023
Translational Psychiatry

Volume: 13, P: 1-10
Combination of NTP with cetuximab inhibited invasion/migration of cetuximab-resistant OSCC cells: Involvement of NF-κB signaling

Jae Won Chang
Sung Un Kang
Chul-Ho Kim
ResearchOpen Access14 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Bacterial contamination of autologous blood salvaged during deceased donor liver transplantation: a prospective observational study

Doyeon Kim
Sangbin Han
Gaab Soo Kim
ResearchOpen Access05 Nov 2024
Scientific Reports

Volume: 14, P: 1-10
Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study

Yohan Park
Ji Won Lee
Won Min Hwang
ResearchOpen Access22 Jan 2024
Scientific Reports

Volume: 14, P: 1-11
Phosphatidylinositol 4,5-bisphosphate (PIP₂) facilitates norepinephrine transporter dimerization and modulates substrate efflux

Phosphatidylinositol 4,5-bisphosphate (PIP₂) directly regulates norepinephrine transporter (NET) dimer stabilization at the plasma membrane. Furthermore, PIP₂ interaction with NET affects efflux.

Dino Luethi
Julian Maier
Harald H. Sitte
ResearchOpen Access17 Nov 2022
Communications Biology

Volume: 5, P: 1-11
S-Nitrosylation of cathepsin B affects autophagic flux and accumulation of protein aggregates in neurodegenerative disorders

Ki-Ryeong Kim
Eun-Jung Cho
Yang-Hee Kim
Research24 Apr 2022
Cell Death & Differentiation

Volume: 29, P: 2137-2150
Relative overhydration is independently associated with left ventricular hypertrophy in dialysis naïve patients with stage 5 chronic kidney disease

Byoung-Geun Han
Jun Young Lee
Jae-Seok Kim
ResearchOpen Access02 Oct 2020
Scientific Reports

Volume: 10, P: 1-11
Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis

Seon-A Choi
Young-Hyun Kim
Kyu-Tae Chang
ResearchOpen Access21 Nov 2018
Cell Death & Differentiation

Volume: 26, P: 1582-1599
Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model

Myung-Hee Moon
Jae-Kyo Jeong
Sang-Youel Park
ResearchOpen Access03 Aug 2012
Experimental & Molecular Medicine

Volume: 44, P: 603-614
Comparative effects of overexpression of p27^Kip1 and p21^Cip1/Waf1 on growth and differentiation in human colon carcinoma cells

Hirofumi Yamamoto
Jae-Won Soh
I Bernard Weinstein
Research19 Jan 1999
Oncogene

Volume: 18, P: 103-115

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