Nature Search

Rank signaling drives basal cell-lineage infidelity leading to mammary tumorigenesis

Here, the authors detail how RANK signaling in basal epithelial cells from the mammary gland alters cell identity by epigenetic remodelling to promote breast tumorigenesis and underscores the therapeutic value of RANK pathway in human breast cancer.

Jaime Redondo-Pedraza
Patricia G. Santamaría
Eva González-Suárez
ResearchOpen Access27 Feb 2026
Nature Communications

P: 1-17
Inhaling: endocannabinoids and food intake

Feeding effects of CB₁ receptors are commonly associated with exogenous cannabinoids, but a study now identifies a circuit by which endocannabinoid activation of CB₁ receptors in the main olfactory bulb regulates normal food intake.

Jaime G Maldonado-Avilés
Ralph J DiLeone
News & Views25 Feb 2014
Nature Neuroscience

Volume: 17, P: 336-337
Water shortages means greening southern European cities won’t be easy

Jaime Madrigal-González
José Miguel Olano
Gabriel Sangüesa-Barreda
Correspondence12 Mar 2024
Nature

Volume: 627, P: 271
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Longitudinal cervicovaginal bacteriome and virome alterations associate with discordant shedding and ART duration in women living with HIV in Peru

Female genital tract (FGT) microbiome dynamics in discordant HIV shedding and long-term antiretroviral therapy are poorly understood. Here, using 125 cervicovaginal specimens collected over two years from 31 women living with HIV in Lima, Peru, Kaelin et al. show that FGT bacteriome and virome patterns over time are linked with discordant shedding and ART duration.

Emily A. Kaelin
Caroline Mitchell
Efrem S. Lim
ResearchOpen Access25 Aug 2025
Nature Communications

Volume: 16, P: 1-16
Vision of the human being in the Stockholm 72 conference: similarities and differences with Christian anthropology

María Zitto Soria
Alberto López Rosado
Jaime Tatay
ResearchOpen Access03 Mar 2026
Humanities and Social Sciences Communications

Volume: 13, P: 1-13
Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands

Rocha and co-authors show that loss of luminal Rank signaling causes abnormal alveolar differentiation and lactation failure. Subsequent pregnancies activate bipotency in basal cells, replacing unfit luminal cells, and restoring lactation.

Ana Sofia Rocha
Alejandro Collado-Solé
Eva González-Suárez
ResearchOpen Access09 Oct 2023
Nature Communications

Volume: 14, P: 1-13
Global spatial risk assessment of sharks under the footprint of fisheries

A global dataset of the satellite-tracked movements of pelagic sharks and fishing fleets show that sharks—and, in particular, commercially important species—have limited spatial refuge from fishing effort.

Nuno Queiroz
Nicolas E. Humphries
David W. Sims
Research24 Jul 2019
Nature

Volume: 572, P: 461-466
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Genomic reconstruction of the SARS-CoV-2 epidemic in England

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
ResearchOpen Access14 Oct 2021
Nature

Volume: 600, P: 506-511
Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

Crhistian-Mario Oblitas
Pablo Demelo-Rodríguez
Hector Meijide Míguez
ResearchOpen Access05 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Reply to: Shark mortality cannot be assessed by fishery overlap alone

Nuno Queiroz
Nicolas E. Humphries
David W. Sims
Research07 Jul 2021
Nature

Volume: 595, P: E8-E16
Reply to: Caution over the use of ecological big data for conservation

Nuno Queiroz
Nicolas E. Humphries
David W. Sims
Research07 Jul 2021
Nature

Volume: 595, P: E20-E28
Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry

José-Manuel Casas-Rojo
Juan-Miguel Antón-Santos
Hector Meijide Míguez
ResearchOpen Access18 Oct 2023
Scientific Reports

Volume: 13, P: 1-18
Expanding the mutation spectrum in 182 Spanish probands with craniosynostosis: identification and characterization of novel TCF12 variants

Beatriz Paumard-Hernández
Julia Berges-Soria
Karen E Heath
Research01 Oct 2014
European Journal of Human Genetics

Volume: 23, P: 907-914
Global patterns of tree density are contingent upon local determinants in the world’s natural forests

Global tree abundance is demonstrated to correlate with latitudinal variables, with tree size and self-thinning strategies impacting current estimates of tree count.

Jaime Madrigal-González
Joaquín Calatayud
Markus Stoffel
ResearchOpen Access13 Jan 2023
Communications Biology

Volume: 6, P: 1-6
The effect of a mindfulness-based therapy on different biomarkers among patients with inflammatory bowel disease: a randomised controlled trial

Rafael González-Moret
Ausias Cebolla
José Miguel Soria
ResearchOpen Access08 Apr 2020
Scientific Reports

Volume: 10, P: 1-7
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
Functional proteomics outlines the complexity of breast cancer molecular subtypes

Angelo Gámez-Pozo
Lucía Trilla-Fuertes
Juan Ángel Fresno Vara
ResearchOpen Access30 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain

María José Iglesias
Daniel Ibarz
M. I. Galán
ResearchOpen Access24 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14
Author Correction: The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain

María José Iglesias
Daniel Ibarz
M. I. Galán
Amendments and CorrectionsOpen Access13 Mar 2025
Scientific Reports

Volume: 15, P: 1

Search

Rank signaling drives basal cell-lineage infidelity leading to mammary tumorigenesis

Inhaling: endocannabinoids and food intake

Water shortages means greening southern European cities won’t be easy

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

A second update on mapping the human genetic architecture of COVID-19

Longitudinal cervicovaginal bacteriome and virome alterations associate with discordant shedding and ART duration in women living with HIV in Peru

Vision of the human being in the Stockholm 72 conference: similarities and differences with Christian anthropology

Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands

Global spatial risk assessment of sharks under the footprint of fisheries

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

SARS-CoV-2 evolution during treatment of chronic infection

Genomic reconstruction of the SARS-CoV-2 epidemic in England

Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

Reply to: Shark mortality cannot be assessed by fishery overlap alone

Reply to: Caution over the use of ecological big data for conservation

Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry

Expanding the mutation spectrum in 182 Spanish probands with craniosynostosis: identification and characterization of novel TCF12 variants

Global patterns of tree density are contingent upon local determinants in the world’s natural forests

The effect of a mindfulness-based therapy on different biomarkers among patients with inflammatory bowel disease: a randomised controlled trial

Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Functional proteomics outlines the complexity of breast cancer molecular subtypes

The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain

Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Author Correction: The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain

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