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Showing 1–4 of 4 results

Advanced filters: Author: Jake VanCampen Clear advanced filters

TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

The authors show that the deletion of ultraconserved TAD boundaries affects gene expression and phenotype, highlighting TAD evolution’s function. Human-specific TAD boundaries reveal a role in brain development and disease.

Mariam Okhovat
Jake VanCampen
Lucia Carbone
ResearchOpen Access07 Dec 2023
Nature Communications

Volume: 14, P: 1-13
Genome-wide analysis of cis-regulatory changes underlying metabolic adaptation of cavefish

Genome-wide epigenomic profiling of liver tissue from one surface and two independent cave populations of Astyanax mexicanus sheds light on regulatory changes underlying metabolic adaptations to the nutrient-deprived cave environment.

Jaya Krishnan
Chris W. Seidel
Nicolas Rohner
Research12 May 2022
Nature Genetics

Volume: 54, P: 684-693
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Debra Van Egeren
Khushi Kohli
Zenta Walther
ResearchOpen Access09 Nov 2022
Scientific Reports

Volume: 12, P: 1-6
PU.1 and MYC transcriptional network defines synergistic drug responses to KIT and LSD1 inhibition in acute myeloid leukemia

Brittany M. Curtiss
Jake VanCampen
Theodore P. Braun
Research19 May 2022
Leukemia

Volume: 36, P: 1781-1793