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Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy

The clinical detection of fluorescent protoporphyrin IX during glioma-resection surgery can be improved via a microscope that pairs stimulated Raman histology and two-photon excitation fluorescence microscopy.

Mustafa Nasir-Moin
Lisa Irina Wadiura
Daniel A. Orringer
Research10 Jul 2024
Nature Biomedical Engineering

Volume: 8, P: 672-688
Axonal synapse sorting in medial entorhinal cortex

Path-length-dependent axonal synapse sorting of local presynaptic axons of excitatory neurons in the rat medial entorhinal cortex results in sequential targeting of inhibitory and excitatory neurons, which are connected by a cellular feedforward inhibition circuit.

Helene Schmidt
Anjali Gour
Moritz Helmstaedter
Research20 Sept 2017
Nature

Volume: 549, P: 469-475
A carbon nanotube tape for serial-section electron microscopy of brain ultrastructure

Electron microscopy requires electrically conductive and grounded samples to provide high-resolution, high-contrast images. Here, Kubota et al. describe a suitable carbon nanotube based tape for automated serial section collection and imaging, as in ATUM-based electron microscopy.

Yoshiyuki Kubota
Jaerin Sohn
Yasuo Kawaguchi
ResearchOpen Access30 Jan 2018
Nature Communications

Volume: 9, P: 1-15