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Showing 1–10 of 10 results

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Chemomechanically antifibrotic stromal cells

Coating mesenchymal stromal cells with a soft gel incorporating specific chemomechanical cues that enhance the production of collagenases enhances the ability of the cells to inhibit aberrant tissue remodelling in mice with fibrotic lungs.

Michael V. Schrodt
James A. Ankrum
News & Views21 Jan 2022
Nature Biomedical Engineering

Volume: 6, P: 6-7
From lectures to the lab: three steps to becoming an undergraduate researcher

Participating in research gives students first-hand experience of a potential career path and provides graduate students and postdocs with important mentoring opportunities.

James Ankrum
Comments & Opinion30 Jul 2018
Nature
Manufacturing of primed mesenchymal stromal cells for therapy

This Review discusses the factors that affect the phenotypes of mesenchymal stromal cells, and the need for standardized assays that provide quality assurance for clinical uses of the cells.

James Q. Yin
Jun Zhu
James A. Ankrum
Reviews28 Jan 2019
Nature Biomedical Engineering

Volume: 3, P: 90-104
Inhibition of aberrant tissue remodelling by mesenchymal stromal cells singly coated with soft gels presenting defined chemomechanical cues

Mesenchymal stromal cells singly coated with a soft conformal gel incorporating specific chemomechanical cues inhibit aberrant tissue remodelling in mice with fibrotic lung injury.

Sing Wan Wong
Chandramohan R. Tamatam
Jae-Won Shin
Research03 Jun 2021
Nature Biomedical Engineering

Volume: 6, P: 54-66
Human Adipocyte Conditioned Medium Promotes In Vitro Fibroblast Conversion to Myofibroblasts

Mariam Y. El-Hattab
Yoshiaki Nagumo
Edward A. Sander
ResearchOpen Access24 Jun 2020
Scientific Reports

Volume: 10, P: 1-11
Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy

Oliver W. Gramlich
Anthony J. Burand
James A. Ankrum
ResearchOpen Access23 May 2016
Scientific Reports

Volume: 6, P: 1-12
Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery

Aloysius J. Klingelhutz
Francoise A. Gourronc
James A. Ankrum
ResearchOpen Access11 Jan 2018
Scientific Reports

Volume: 8, P: 1-12
Mesenchymal stem cells: immune evasive, not immune privileged

James A Ankrum
Joon Faii Ong
Jeffrey M Karp
Reviews23 Feb 2014
Nature Biotechnology

Volume: 32, P: 252-260
Performance-enhanced mesenchymal stem cells via intracellular delivery of steroids

James A. Ankrum
Riddhi G. Dastidar
Jeffrey M. Karp
ResearchOpen Access10 Apr 2014
Scientific Reports

Volume: 4, P: 1-13
Engineering cells with intracellular agent–loaded microparticles to control cell phenotype

James A Ankrum
Oscar R Miranda
Jeffrey M Karp
Protocols09 Jan 2014
Nature Protocols

Volume: 9, P: 233-245