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Showing 1–50 of 61 results

Advanced filters: Author: James Cerhan Clear advanced filters

Genome-wide association study of event-free survival in follicular lymphoma patients treated with front-line immunochemotherapy

Hervé Ghesquières
Youenn Drouet
James R. Cerhan
ResearchOpen Access09 Jan 2026
Blood Cancer Journal

P: 1-11
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma

James Cerhan and colleagues report genome-wide association and meta-analysis studies to identify genetic susceptibility loci for diffuse large B cell lymphoma. They identify four loci that influence genetic susceptibility to this B cell malignancy.

James R Cerhan
Sonja I Berndt
Stephen J Chanock
Research28 Sept 2014
Nature Genetics

Volume: 46, P: 1233-1238
Transcriptomic classification of diffuse large B-cell lymphoma identifies a high-risk activated B-cell-like subpopulation with targetable MYC dysregulation

Researchers identified 7 biological group of diffuse large B-cell lymphoma, one with poor prognosis. They developed a gene expression classifier to detect these groups, potentially improving prognosis and future treatments for the high-risk patients.

Matthew E. Stokes
Kerstin Wenzl
Anita K. Gandhi
ResearchOpen Access08 Aug 2024
Nature Communications

Volume: 15, P: 1-19
Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia

Chronic lymphocytic leukemia is a highly inheritable cancer. Here the authors conduct a metaanalysis of four genome-wide association studies and identify three novel loci located near EOMES, SERPINB6 and LPPassociated with risk of this disease.

Sonja I. Berndt
Nicola J. Camp
Susan L. Slager
ResearchOpen Access09 Mar 2016
Nature Communications

Volume: 7, P: 1-9
A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Marginal zone lymphoma (MZL) is a common subtype of B-cell non-Hodgkin lymphoma. Here the authors carry out a two-stage genome-wide association study in over 8,000 Europeans and identify two new MZL risk loci at chromosome 6p, implicating the major histocompatibility complex in the disease for the first time.

Joseph Vijai
Zhaoming Wang
Alexandra Nieters
ResearchOpen Access08 Jan 2015
Nature Communications

Volume: 6, P: 1-7
Integrated genomics with refined cell-of-origin subtyping distinguishes subtype-specific mechanisms of treatment resistance and relapse in diffuse large B-cell lymphoma

Janek S. Walker
Kerstin Wenzl
Anne J. Novak
ResearchOpen Access12 Jul 2025
Blood Cancer Journal

Volume: 15, P: 1-14
Incidental vs. symptomatic diagnosis of follicular lymphoma: implications of earlier detection

Suheil Albert Atallah-Yunes
Matthew J. Rees
Thomas E. Witzig
ResearchOpen Access03 Jul 2025
Blood Cancer Journal

Volume: 15, P: 1-6
Multiomic analysis identifies a high-risk signature that predicts early clinical failure in DLBCL

Kerstin Wenzl
Matthew E. Stokes
Anne J. Novak
ResearchOpen Access20 Jun 2024
Blood Cancer Journal

Volume: 14, P: 1-11
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

Susan Slager and colleagues report a meta-analysis of genome-wide association studies for chronic lymphocytic leukemia (CLL). They identify nine loci newly associated with CLL.

Sonja I Berndt
Christine F Skibola
Susan L Slager
Research16 Jun 2013
Nature Genetics

Volume: 45, P: 868-876
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia has a hereditary component, much of which remains to be identified. Here, the authors perform a genome-wide association study and find new risk loci for the disease, which are associated with genes involved in immune function.

Philip J. Law
Sonja I. Berndt
Susan Slager
ResearchOpen Access06 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Plasma organochlorine levels and prostate cancer risk

Kristan J Aronson
James W L Wilson
Alvara Morales
Research10 Jun 2009
Journal of Exposure Science & Environmental Epidemiology

Volume: 20, P: 434-445
Risk of lymphoid malignancy associated with cancer predisposition genes

Nicholas J. Boddicker
Raphael Mwangi
James R. Cerhan
ResearchOpen Access19 Apr 2025
Blood Cancer Journal

Volume: 15, P: 1-9
DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas

Melissa A. Hopper
Abigail R. Dropik
Anne J. Novak
ResearchOpen Access09 Oct 2024
Blood Cancer Journal

Volume: 14, P: 1-10
No association of germline alteration of MSR1 with prostate cancer risk

Liang Wang
Shannon K McDonnell
Stephen N Thibodeau
Research07 Sept 2003
Nature Genetics

Volume: 35, P: 128-129
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32

Christine Skibola and colleagues identify variants at 6p21.32 associated with risk of follicular lymphoma, providing further support that variation in the MHC region influences risk of this disease. They also replicate previously reported risk variants for chronic lymphocytic leukemia.

Lucia Conde
Eran Halperin
Christine F Skibola
Research18 Jul 2010
Nature Genetics

Volume: 42, P: 661-664
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research10 Feb 2008
Nature Genetics

Volume: 40, P: 281-283
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia

Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a non-Hodgkin-type B cell lymphoma. Here, the authors identify two risk loci for WM/LPL in a two-stage GWAS involving a family-oversampling approach and provide evidence for a functional role of the non-coding SNP rs116446171.

Mary L. McMaster
Sonja I. Berndt
Neil E. Caporaso
ResearchOpen Access10 Oct 2018
Nature Communications

Volume: 9, P: 1-12
CHIP amplifies the risk of lymphoid malignancies in individuals with monoclonal B-cell lymphocytosis (MBL)

Nicholas J. Boddicker
Tait D. Shanafelt
Susan L. Slager
ResearchOpen Access06 Nov 2025
Blood Cancer Journal

Volume: 15, P: 1-8
PET2 response associated with survival in newly diagnosed diffuse large B-cell lymphoma: results of two independent prospective cohorts

Sanjal H. Desai
Levi Pederson
Grzegorz S. Nowakowski
ResearchOpen Access03 May 2022
Blood Cancer Journal

Volume: 12, P: 1-6
Clinical characteristics and outcomes of primary versus secondary gastrointestinal mantle cell lymphoma

Alessia Castellino
Aung M. Tun
Grzegorz S. Nowakowski
ResearchOpen Access07 Jan 2021
Blood Cancer Journal

Volume: 11, P: 1-8
Patterns of therapy initiation during the first decade for patients with follicular lymphoma who were observed at diagnosis in the rituximab era

Arushi Khurana
Raphael Mwangi
Grzegorz S. Nowakowski
ResearchOpen Access17 Jul 2021
Blood Cancer Journal

Volume: 11, P: 1-6
Somatic copy number gains in MYC, BCL2, and BCL6 identifies a subset of aggressive alternative-DH/TH DLBCL patients

Jordan E. Krull
Kerstin Wenzl
Anne J. Novak
ResearchOpen Access09 Nov 2020
Blood Cancer Journal

Volume: 10, P: 1-8
Detection and prevalence of monoclonal gammopathy of undetermined significance: a study utilizing mass spectrometry-based monoclonal immunoglobulin rapid accurate mass measurement

David Murray
Shaji K. Kumar
S. Vincent Rajkumar
ResearchOpen Access13 Dec 2019
Blood Cancer Journal

Volume: 9, P: 1-7
Defining cure in multiple myeloma: a comparative study of outcomes of young individuals with myeloma and curable hematologic malignancies

Praful Ravi
Shaji K. Kumar
S. Vincent Rajkumar
ResearchOpen Access28 Feb 2018
Blood Cancer Journal

Volume: 8, P: 1-7
High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing

Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of functional SNPs at disease risk loci.

Peng Zhang
Ji-Han Xia
Liang Wang
ResearchOpen Access22 May 2018
Nature Communications

Volume: 9, P: 1-12
Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

Bjoern Chapuy
Chip Stewart
Margaret A. Shipp
Amendments and Corrections28 Jun 2018
Nature Medicine

Volume: 24, P: 1290-1291
Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

Bjoern Chapuy
Chip Stewart
Margaret A. Shipp
Amendments and Corrections28 Jun 2018
Nature Medicine

Volume: 24, P: 1292
Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes

Sonja I. Berndt
Joseph Vijai
Nathaniel Rothman
Research22 Oct 2022
Leukemia

Volume: 36, P: 2835-2844
Association of elevated serumfree light chains with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis

Alyssa I. Clay-Gilmour
Abdul R. Rishi
Celine M. Vachon
ResearchOpen Access05 Aug 2019
Blood Cancer Journal

Volume: 9, P: 1-8
Subsets of follicular lymphoma 3B have divergent outcomes: results from the prospective multicenter MER and LEO cohorts

Patrizia Mondello
Brianna Negaard
Stephen M. Ansell
ResearchOpen Access08 Aug 2025
Blood Cancer Journal

Volume: 15, P: 1-8
Evolving treatment patterns and improved outcomes in relapsed/refractory mantle cell lymphoma: a prospective cohort study

Allison M. Bock
Jennifer J. Gile
Yucai Wang
ResearchOpen Access13 Nov 2023
Blood Cancer Journal

Volume: 13, P: 1-9
Advancing efficacy prediction for electronic health records based emulated trials in repurposing heart failure therapies

Nansu Zong
Shaika Chowdhury
James R. Cerhan
ResearchOpen Access24 May 2025
npj Digital Medicine

Volume: 8, P: 1-13
The epidemiology of non-Hodgkin's lymphoma

Susan G Fisher
Richard I Fisher
Reviews23 Aug 2004
Oncogene

Volume: 23, P: 6524-6534
History of autoimmune conditions and lymphoma prognosis

Geffen Kleinstern
Matthew J. Maurer
James R. Cerhan
ResearchOpen Access01 Aug 2018
Blood Cancer Journal

Volume: 8, P: 1-10
Synoptic reporting by summarizing cancer pathology reports using large language models

Sivaraman Rajaganapathy
Shaika Chowdhury
Nansu Zong
ResearchOpen Access01 Apr 2025
npj Health Systems

Volume: 2, P: 1-12
Genomic characterization of chronic lymphocytic leukemia in patients of African ancestry

Cecilia Bonolo de Campos
Chantal E. McCabe
Esteban Braggio
ResearchOpen Access06 Feb 2025
Blood Cancer Journal

Volume: 15, P: 1-8
Low-frequency and rare genetic variants associated with rheumatoid arthritis risk

Rheumatoid arthritis has a substantial genetic component, some of which is associated with the presence of low-frequency or rare variants. Next-generation sequencing in large and well-defined cohorts can continue to identify these variants and thereby contribute to the future prediction, diagnosis and treatment of rheumatoid arthritis.

Vanessa L. Kronzer
Jeffrey A. Sparks
James R. Cerhan
Reviews27 Mar 2024
Nature Reviews Rheumatology

Volume: 20, P: 290-300
Relationship among three common hematological premalignant conditions

Nicholas J. Boddicker
Sameer A. Parikh
Susan L. Slager
ResearchOpen Access05 May 2023
Leukemia

Volume: 37, P: 1719-1722
Genetic risk factors for COVID-19 and influenza are largely distinct

Genome-wide analyses identify variants in B3GALT5 and ST6GAL1 associated with influenza susceptibility. Knockdown of ST6GAL1 in cell culture reduces influenza infectivity, likely by interfering with the glycoprotein modifications required for viral entry.

Jack A. Kosmicki
Anthony Marcketta
Manuel A. R. Ferreira
ResearchOpen Access05 Aug 2024
Nature Genetics

Volume: 56, P: 1592-1596
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

Comprehensive integration of mutational and structural alterations in clinically-annotated DLBCL patient samples provides a novel molecular classification of the disease.

Bjoern Chapuy
Chip Stewart
Margaret A. Shipp
Research30 Apr 2018
Nature Medicine

Volume: 24, P: 679-690
Associations of history of vaccination and hospitalization due to infection with risk of monoclonal B-cell lymphocytosis

Nicholas J. Boddicker
Sara J. Achenbach
Susan L. Slager
ResearchOpen Access15 Feb 2022
Leukemia

Volume: 36, P: 1404-1407
Mosaic chromosomal alterations (mCAs) in individuals with monoclonal B-cell lymphocytosis (MBL)

Aswin Sekar
Rosalie Griffin
Susan L. Slager
ResearchOpen Access06 Nov 2024
Blood Cancer Journal

Volume: 14, P: 1-8
Relationship between BCL2 mutations and follicular lymphoma outcome in the chemoimmunotherapy era

Cristina Correia
Matthew J. Maurer
Scott H. Kaufmann
ResearchOpen Access17 May 2023
Blood Cancer Journal

Volume: 13, P: 1-9
High-dimensional and single-cell transcriptome analysis of the tumor microenvironment in angioimmunoblastic T cell lymphoma (AITL)

Joshua C. Pritchett
Zhi-Zhang Yang
Stephen M. Ansell
Research06 Jul 2021
Leukemia

Volume: 36, P: 165-176
Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma

Patrizia Mondello
Angelo Fama
Stephen M. Ansell
ResearchOpen Access15 Jul 2021
Blood Cancer Journal

Volume: 11, P: 1-11
Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans

Geffen Kleinstern
J. Brice Weinberg
Susan L. Slager
ResearchOpen Access20 Jul 2021
Leukemia

Volume: 36, P: 119-125
Vitamin D insufficiency is associated with an increased risk of early clinical failure in follicular lymphoma

S I Tracy
M J Maurer
J R Cerhan
ResearchOpen Access25 Aug 2017
Blood Cancer Journal

Volume: 7, P: e595
Intake of coffee, caffeine and other methylxanthines and risk of Type I vs Type II endometrial cancer

S Uccella
A Mariani
J R Cerhan
ResearchOpen Access10 Sept 2013
British Journal of Cancer

Volume: 109, P: 1908-1913
Targeting of inflammatory pathways with R2CHOP in high-risk DLBCL

Keenan T. Hartert
Kerstin Wenzl
Anne J. Novak
Research05 Mar 2020
Leukemia

Volume: 35, P: 522-533
Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

Linda B. Baughn
Kathryn Pearce
S. Vincent Rajkumar
ResearchOpen Access10 Oct 2018
Blood Cancer Journal

Volume: 8, P: 1-10

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