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Showing 1–50 of 170 results

Advanced filters: Author: James Kemp Clear advanced filters

Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release

Distal mutations, though far from the active site, enhance Kemp eliminase catalysis by tuning conformational dynamics that facilitate substrate binding and product release, thereby promoting the full catalytic cycle.

Niayesh Zarifi
Pooja Asthana
Roberto A. Chica
ResearchOpen Access30 Sept 2025
Nature Communications

Volume: 16, P: 1-13
Elliptical Polarization by Surface-layer Scattering

JAMES C. KEMP
RAMON D. WOLSTENCROFT
Research21 May 1971
Nature

Volume: 231, P: 170-171
Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico

Kemp eliminases are artificial enzymes that catalyze the concerted deprotonation and ring-opening of benzisoxazoles. Here, the authors use room-temperature X-ray crystallography to investigate changes to the conformational ensemble of the Kemp eliminase HG3 along a directed evolutionary trajectory, and develop an experimentally guided, ensemble-based computational enzyme design procedure.

Aron Broom
Rojo V. Rakotoharisoa
Roberto A. Chica
ResearchOpen Access23 Sept 2020
Nature Communications

Volume: 11, P: 1-10
New results from optical polarimetry of Saturn's rings

Paul E. Johnson
James C. Kemp
Mark S. Barbour
Research10 Jan 1980
Nature

Volume: 283, P: 146-149
Circular Polarization: Jupiter and Other Planets

JAMES C. KEMP
RAMON D. WOLSTENCROFT
JOHN B. SWEDLUND
Research16 Jul 1971
Nature

Volume: 232, P: 165-168
Physical Sciences: Circularly Polarized Visible Light from Jupiter

JAMES C. KEMP
JOHN B. SWEDLUND
RAMON D. WOLSTENCROFT
Research21 May 1971
Nature

Volume: 231, P: 169-170
Evidence for a 39-d period in Cyg X – 1

JAMES C. KEMP
LEONARD C. HERMAN
MARK S. BARBOUR
Research17 Nov 1977
Nature

Volume: 270, P: 227-228
Capacitation of Frog Sperm

C. ALEX SHIVERS
JUDITH M. JAMES
Research11 Jul 1970
Nature

Volume: 227, P: 183-184
The helical s constant for alanine in water derived from template-nucleated helices

D. S. Kemp
James G. Boyd
Christopher C. Muendel
Research01 Aug 1991
Nature

Volume: 352, P: 451-454
Potassium-40 isotopic evidence for an extant pre-giant-impact component of Earth’s mantle

Some mafic rocks have a ⁴⁰K/³⁹K ratio lower than all other terrestrial samples, according to isotopic composition analyses, suggesting parts of Earth’s mantle have retained their composition prior to the Moon-forming impact to the present day.

Da Wang
Nicole X. Nie
Richard W. Carlson
Research14 Oct 2025
Nature Geoscience

Volume: 18, P: 1174-1179
Can galaxy warps be used to provide constraints on halo properties?

George Lake
James W.-K. Mark
Research23 Oct 1980
Nature

Volume: 287, P: 705-706
A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferons

Jon Weil
Charles J. Epstein
Sidney E. Grossberg
Research03 Feb 1983
Nature

Volume: 301, P: 437-439
Release and activation of platelet latent TGF–β in blood clots during dissolution with plasmin

David J. Grainger
Lalage Wakefield
James C. Metcalfe
Research01 Sept 1995
Nature Medicine

Volume: 1, P: 932-937
Mouse spleen and IgD-secreting plasmacytomas contain multiple IgD δ chain RNAs

Leona Fitzmaurice
James Owens
J. Frederic Mushinski
Research01 Apr 1982
Nature

Volume: 296, P: 459-462
Purified human growth hormone from E. coli is biologically active

Kenneth C. Olson
James Fenno
Nowell Stebbing
Research01 Oct 1981
Nature

Volume: 293, P: 408-411
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Latest Miocene benthic δ¹⁸O changes, global ice volume, sea level and the ‘Messinian salinity crisis’

David A. Hodell
Kristin M. Elmstrom
James P. Kennett
Research03 Apr 1986
Nature

Volume: 320, P: 411-414
Physical Properties of Bedding That May Increase Risk of Sudden Infant Death Syndrome in Prone-Sleeping Infants

James S Kemp
Verna E Nelson
Bradley T Thach
Research01 Jul 1994
Pediatric Research

Volume: 36, P: 7-11
A line in the sea

James A. Yoder
Steven G. Ackleson
William M. Balch
Research20 Oct 1994
Nature

Volume: 371, P: 689-692
Photometry of the zodiacal light in the near infrared

G. R. HOPKINSON
YVONNE ELSWORTH
J. F. JAMES
Research25 Oct 1974
Nature

Volume: 251, P: 694
Regulation of transcription in expressed and unexpressed mating type cassettes of yeast

Amar J. S. Klar
Jeffrey N. Strathern
James B. Hicks
Research22 Jan 1981
Nature

Volume: 289, P: 239-244
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

A study of SARS-CoV-2 variants examining their transmission, infectivity, and potential resistance to therapies provides insights into the biology of the Delta variant and its role in the global pandemic.

Petra Mlcochova
Steven A. Kemp
Ravindra K. Gupta
ResearchOpen Access06 Sept 2021
Nature

Volume: 599, P: 114-119
Role of transition-metal catalysis in the formation of natural gas

Frank D. Mango
J. W. Hightower
Alan T. James
Research07 Apr 1994
Nature

Volume: 368, P: 536-538
Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice

David J. Grainger
Paul R. Kemp
James C. Metcalfe
Research11 Aug 1994
Nature

Volume: 370, P: 460-462
Isolation of malignant and functional Ly 1⁺ T-cell clones from B-cell lymphomas

Carol L. Reinisch
Amy P. Sing
John D. Kemp
Research08 Jul 1982
Nature

Volume: 298, P: 176-178
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Adsorption of Trace Amounts of Cations on Anion Exchange Resins by the Formation of Insoluble Salts

R. H. JAMES
G. A. WELCH
Research28 Jan 1956
Nature

Volume: 177, P: 183-184
Neural Volleying: Upper Frequency Limits detectable in the Auditory System

JAMES C. BOUDREAU
Research18 Dec 1965
Nature

Volume: 208, P: 1237-1238
Three-dimensional structure of CheY, the response regulator of bacterial chemotaxis

Ann M. Stock
James M. Mottonen
Clarence E. Schutt
Research23 Feb 1989
Nature

Volume: 337, P: 745-749
The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis

David J. Grainger
Paul R. Kemp
Anoop Chauhan
Research01 Jan 1995
Nature Medicine

Volume: 1, P: 74-79
SARS-COV-2 antibody responses to AZD1222 vaccination in West Africa

Data on immune response to the SARS-COV-2 AZD1222 vaccine are limited in African populations. Here, the authors show immunogenicity of the AZD1222 vaccine in two independent cohorts from West Africa, including seroprevalence levels prior to vaccine rollout in January 2021.

Adam Abdullahi
David Oladele
Ravindra K. Gupta
ResearchOpen Access17 Oct 2022
Nature Communications

Volume: 13, P: 1-11
Possible methane-induced polar warming in the early Eocene

L. Cirbus Sloan
James C. G. Walker
James C. Zachos
Research28 May 1992
Nature

Volume: 357, P: 320-322
Distinctive mammal-like reptile from Mexico and its bearing on the phylogeny of the Tritylodontidae

James M. Clark
James A. Hopson
Research30 May 1985
Nature

Volume: 315, P: 398-400
Tamoxifen elevates transforming growth factor–β and suppresses diet–induced formation of lipid lesions in mouse aorta

David J. Grainger
Christine M. Witchell
James C. Metcalfe
Research01 Oct 1995
Nature Medicine

Volume: 1, P: 1067-1073
Cerebral Glucose Utilization During Aerobic Metabolism in Fetal Sheep

Nicholas G Tsoulos
Jack M Schneider
Frederick C Battaglia
Research01 Mar 1972
Pediatric Research

Volume: 6, P: 182-186
Experimental Neonatal Syphilis. I. Evidence of Resistance to Symptomatic Infection in Neonatal Rabbits following Intradermal Inoculation with Treponema pallidum (Nichols Strain)

Darlene Gamboa
James N Miller
Research01 Oct 1984
Pediatric Research

Volume: 18, P: 965-971
Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

Ke Shuai
Andrew Ziemiecki
James E. Darnell
Research09 Dec 1993
Nature

Volume: 366, P: 580-583
Please write legibly

James Bottomley
Correspondence01 Feb 1996
Nature

Volume: 379, P: 396
Inexpressible trinucleotides

James McClellan
Sarah Newbury
Correspondence01 Feb 1996
Nature

Volume: 379, P: 396
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Vaccination is effective in protecting from COVID-19. Here the authors report immune responses and breakthrough infections in twice-vaccinated patients receiving anti-TNF treatments for inflammatory bowel disease, and find dampened vaccine responses that implicate the need of adapted vaccination schedules for these patients.

Simeng Lin
Nicholas A. Kennedy
Jeannie Bishop
ResearchOpen Access16 Mar 2022
Nature Communications

Volume: 13, P: 1-14
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

The spike protein of the Omicron variant of SARS-CoV-2 has a higher affinity for ACE2 than Delta, and a marked change in its antigenicity increases Omicron’s evasion of therapeutic and vaccine-elicited neutralizing antibodies.

Bo Meng
Adam Abdullahi
Ravindra K. Gupta
ResearchOpen Access01 Feb 2022
Nature

Volume: 603, P: 706-714
Expression of cloned β-endorphin gene sequences by Escherichia coli

John Shine
Ivy Fettes
John D. Baxter
Research12 Jun 1980
Nature

Volume: 285, P: 456-461
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

An expanded GWAS of birth weight and subsequent analysis using structural equation modeling and Mendelian randomization decomposes maternal and fetal genetic contributions and causal links between birth weight, blood pressure and glycemic traits.

Nicole M. Warrington
Robin N. Beaumont
Rachel M. Freathy
Research01 May 2019
Nature Genetics

Volume: 51, P: 804-814
Two contrasting Phanerozoic orogenic systems revealed by hafnium isotope data

Two types of mountain-forming systems exist on Earth — external orogens form during oceanic–continental plate collisions and internal orogens form where continental plates collide. Hafnium isotope data from orogens worldwide show that each has produced a distinctive signature over the past 550 Myr, reflecting the contrasting subduction geometry in each setting.

William J. Collins
Elena A. Belousova
J. Brendan Murphy
Research17 Apr 2011
Nature Geoscience

Volume: 4, P: 333-337
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

A high-resolution, global atlas of mortality of children under five years of age between 2000 and 2017 highlights subnational geographical inequalities in the distribution, rates and absolute counts of child deaths by age.

Roy Burstein
Nathaniel J. Henry
Simon I. Hay
ResearchOpen Access16 Oct 2019
Nature

Volume: 574, P: 353-358
High resolution structures of HIV-1 RT from four RT–inhibitor complexes

Jingshan Ren
Robert Esnouf
David Stammers
Research01 Apr 1995
Nature Structural Biology

Volume: 2, P: 293-302
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Transancestral GWAS meta-analysis in 160,420 individuals identifies 139 loci associated with refractive error, including myopia. Newly identified genes implicate pathways involved in eye growth and light signaling cascades.

Milly S. Tedja
Robert Wojciechowski
Caroline C. W. Klaver
Research28 May 2018
Nature Genetics

Volume: 50, P: 834-848
On the Circular Polarization of Sco X-1 and the Adjacent Sky

JAMES C. KEMP
Correspondence04 Dec 1972
Nature Physical Science

Volume: 240, P: 103-104
CD22 regulates thymus-independent responses and the lifespan of B cells

Kevin L. Otipoby
Kristin B. Andersson
Edward A. Clark
Research26 Dec 1996
Nature

Volume: 384, P: 634-637
A bacterial virulence determinant encoded by lysogenic coliphage λ

James J. Barondess
Jon Beckwfth
Research30 Aug 1990
Nature

Volume: 346, P: 871-874

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