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Showing 1–8 of 8 results
Advanced filters: Author: James M. Dupree Clear advanced filters

  • On 11 March 2020, the World Health Organization declared SARS-CoV-2 and its associated disease, COVID-19, a global pandemic. Across the world, governments took action to slow the spread and hospitals rushed to accommodate an influx of patients with this highly infectious and lethal disease. The urology departments in Ann Arbor, Michigan, USA, and Herlev and Gentofte, Copenhagen, Denmark — which are linked by the pre-existing CopMich Collaborative — had to respond with massive changes to the organization, staffing and workload of their teams. In this Viewpoint, authors from different urological subspecialties and at different career stages reflect on their experiences during the pandemic. Although their countries’ responses to the COVID-19 pandemic differed radically, the similarities between the responses in Copenhagen and Michigan demonstrate the universal characteristics of medicine and the value of teamwork, flexibility and collaboration.

    • Juan J. Andino
    • James M. Dupree
    • Daniela Wittmann
    Reviews
    Nature Reviews Urology
    Volume: 17, P: 493-498

  • Sexual health, even into older age, is important to many people. A new paper reports that older men with hypogonadism who take testosterone experience significant improvements in sexual activity, erectile function and libido. Testosterone therapy has long been a matter of interest (and controversy) for physicians, and this study is a landmark one that is worthy of further discussion.

    • James M. Dupree
    News & Views
    Nature Reviews Urology
    Volume: 13, P: 244-245

  • Testosterone replacement therapy use has been increasing; however, a gap exists in patients' understanding of this therapy and its associated risks, and available online resources might not be bridging this gap. Action should be taken to provide patients with accessible credible information.

    • Yooni A. Yi
    • James M. Dupree
    News & Views
    Nature Reviews Urology
    Volume: 14, P: 332-333

  • Historically, the use of testosterone supplementation therapy (TST) for hypogonadism in men with prostate cancer has been limited by concerns that such treatment might cause progression of this androgen-dependent cancer; however, the contemporary literature indicates that TST in men with prostate cancer can be safe and, contrary to traditional thinking, that TST might actually reduce the risk of prostate cancer development. In this opinion piece, Larry Lipshultz and colleagues discuss the evidence supporting TST—in contrast with the lack of evidence against this approach—in hypogonodal men with prostate cancer.

    • James M. Dupree
    • Gavin M. Langille
    • Larry I. Lipshultz
    Reviews
    Nature Reviews Urology
    Volume: 11, P: 526-530

  • Varicocele is the most common correctable cause of male infertility, but some men with varicoceles are able to father children, even without intervention, and so the link between varicoceles and male infertility remains a matter of debate. Oxidative stress seems to be a central mechanism of testicular damage; however, no single theory to explain the differential effect of varicoceles on infertility has been suggested. In this Review, a panel of expert authors discuss the epidemiology and pathophysiology of varicocele-related infertility, and consider the optimal treatment for men with varicocele.

    • Christian Fuglesang S. Jensen
    • Peter Østergren
    • Mikkel Fode
    Reviews
    Nature Reviews Urology
    Volume: 14, P: 523-533