Quantitative polymerase chain reaction allows the real-time detection of nucleic acids in human samples, representing a gold standard for infection detection, but it cannot be easily converted into a point-of-care approach. Here a strategy is proposed to leverage plasmonic polymerase chain reaction to achieve multiplexed, fluorescence detection of SARS-CoV-2 RNA from human saliva and nasal specimen, showing promise as a point-of-care approach.
- Nicole R. Blumenfeld
- Michael Anne E. Bolene
- Samuel K. Sia
