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Showing 1–5 of 5 results
Advanced filters: Author: James W. Satterlee Clear advanced filters

  • Grass ligules comprise the boundary between the leaf base and the photosynthetic blade; their homology has been debated for over 200 years. Cell-specific gene expression analyses suggest that ligules are homologous to the margins of the leaf base.

    • James W. Satterlee
    • Lukas J. Evans
    • Michael J. Scanlon
    ResearchOpen Access
    Nature Plants
    Volume: 9, P: 720-732

  • This study describes the integrative analysis of 111 reference human epigenomes, profiled for histone modification patterns, DNA accessibility, DNA methylation and RNA expression; the results annotate candidate regulatory elements in diverse tissues and cell types, their candidate regulators, and the set of human traits for which they show genetic variant enrichment, providing a resource for interpreting the molecular basis of human disease.

    • Anshul Kundaje
    • Wouter Meuleman
    • Manolis Kellis
    ResearchOpen Access
    Nature
    Volume: 518, P: 317-330

  • Rigorous record-keeping and quality control are required to ensure the quality, reproducibility and value of imaging data. The 4DN Initiative and BINA here propose light Microscopy Metadata Specifications that extend the OME Data Model, scale with experimental intent and complexity, and make it possible for scientists to create comprehensive records of imaging experiments.

    • Mathias Hammer
    • Maximiliaan Huisman
    • Caterina Strambio-De-Castillia
    Comments & Opinion
    Nature Methods
    Volume: 18, P: 1427-1440