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Showing 1–26 of 26 results
Advanced filters: Author: Jamie N. Justice Clear advanced filters

  • The $101 million XPRIZE Healthspan is a 7-year global competition to catalyze the development of interventions to restore function lost to age-related decline of multiple organ systems in humans. Jamie Justice, executive director of the XPRIZE Healthspan competition, introduces the prize and invites the community to help to shape the first phase of the competition.

    • Jamie N. Justice
    Comments & Opinion
    Nature Aging
    Volume: 4, P: 165-166

  • A new study considers how disruption to energy systems is experienced and takes on meaning. On the basis of workshop data, the study finds that public views of heat decarbonization in the United Kingdom are shaped by relationships to family, cultural expectations, housing and financial position.

    • Gareth Hugh Thomas
    • Jack Flower
    • Nick Pidgeon
    ResearchOpen Access
    Nature Energy
    Volume: 9, P: 570-579

  • Aiming for declining global temperatures can limit long-term climate risks compared with a mere stabilization of global warming, including sea-level rise and cryosphere changes.

    • Carl-Friedrich Schleussner
    • Gaurav Ganti
    • Joeri Rogelj
    ResearchOpen Access
    Nature
    Volume: 634, P: 366-373

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • In the past 5 years, a huge amount of untreated wastewater has been released into English waterways. An analysis of the communication used by the water utilities shows that they have employed strategies used by large polluting industries in the past, prolonging the consequences of this environmental disaster.

    • Alex T. Ford
    • Andrew C. Singer
    • Jamie Woodward
    ResearchOpen Access
    Nature Water
    Volume: 3, P: 231-243

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • Post-international travel quarantine has been widely implemented to mitigate SARS-CoV-2 transmission, but the impacts of such policies are unclear. Here, the authors used linked genomic and contact tracing data to assess the impacts of a 14-day quarantine on return to England in summer 2020.

    • Dinesh Aggarwal
    • Andrew J. Page
    • Ewan M. Harrison
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

    • Dami A. Collier
    • Anna De Marco
    • Ravindra K. Gupta
    Research
    Nature
    Volume: 593, P: 136-141

  • Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

    • Steven A. Kemp
    • Dami A. Collier
    • Ravindra K. Gupta
    Research
    Nature
    Volume: 592, P: 277-282

  • Paediatric therapy-related myeloid neoplasms (tMN) have a dismal prognosis and have not been comprehensively profiled. Here the authors characterise the molecular landscape of 84 paediatric tMN patients, and find that, unlike adult tMNs, these do not emerge from pre-existing clones and that MECOM dysregulation is frequent.

    • Jason R. Schwartz
    • Jing Ma
    • Jeffery M. Klco
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • On 1–2 November 2024, the annual Biomarkers of Aging conference welcomed academic and industry scientists, and partners from governmental and nongovernmental organizations, to Harvard Medical School in Boston, USA, to discuss new insights into measuring and monitoring human aging, with the aim of clinical translation. In this Meeting Report, we summarize the conference and offer potential future directions for the Biomarkers of Aging Consortium and the longevity science community at large.

    • Erik Jacques
    • Chiara Herzog
    • Vadim N. Gladyshev
    News & Views
    Nature Aging
    Volume: 5, P: 539-543

  • In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

    • Dinesh Aggarwal
    • Ben Warne
    • Ian G. Goodfellow
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • Biomarkers of aging have potential to accelerate the clinical translation of interventions that promote healthy aging but are currently limited to research. The authors identify six barriers to be overcome to enable biomarker translation, providing a roadmap to clinical implementation.

    • Chiara M. S. Herzog
    • Ludger J. E. Goeminne
    • Vadim N. Gladyshev
    Reviews
    Nature Aging
    Volume: 4, P: 1372-1383

  • Robust validation of biomarkers of aging will be critical to their clinical translation; here, authors review the key challenges and propose recommendations to overcome them.

    • Mahdi Moqri
    • Chiara Herzog
    • Luigi Ferrucci
    Reviews
    Nature Medicine
    Volume: 30, P: 360-372

  • Open scholarship has transformed research, and introduced a host of new terms in the lexicon of researchers. The ‘Framework for Open and Reproducible Research Teaching’ (FORRT) community presents a crowdsourced glossary of open scholarship terms to facilitate education and effective communication between experts and newcomers.

    • Sam Parsons
    • Flávio Azevedo
    • Balazs Aczel
    Comments & Opinion
    Nature Human Behaviour
    Volume: 6, P: 312-318

  • Indigenous peoples are still underrepresented in genetic research. Here, the authors propose an ethical framework consisting of six major principles that encourages researchers and Indigenous communities to build strong and equal partnerships to increase trust, engagement and diversity in genomic studies.

    • Katrina G. Claw
    • Matthew Z. Anderson
    • Joseph M. Yracheta
    ReviewsOpen Access
    Nature Communications
    Volume: 9, P: 1-7