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Advanced filters: Author: Jamie R. Kuhar Clear advanced filters

  • Opioid receptors are important modulators of nociceptive pain. Here the authors show that opioid receptor activation recruits peroxiredoxin 6 (PRDX6) to the receptor-Gαi complex by c-Jun N-terminal kinase, resulting in Gαi depalmitoylation and enhanced receptor-Gαi association.

    • Selena S. Schattauer
    • Benjamin B. Land
    • Charles Chavkin
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14