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Showing 1–3 of 3 results
Advanced filters: Author: Jan Kutner Clear advanced filters

  • Treatment strategy of solid tumors requires continuous development. Here the authors develop a Macrophage Drug Conjugate (MDC) platform by loading ferritin-drug complexes to macrophages. MDC transfers the ferritin to cancer cells via ‘TRAnsfer of Iron binding protein’ (TRAIN) process and reduces tumor volume in various mouse tumor models.

    • Bartlomiej Taciak
    • Maciej Bialasek
    • Magdalena Krol
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-30

  • This protocol enables the study of protein complexes by trapping them in virus-like particles and thereby preserving cellular integrity. The Virotrap protocol is complemented by SFINX, an online data analysis tool for interactomics studies.

    • Kevin Titeca
    • Emmy Van Quickelberghe
    • Sven Eyckerman
    Protocols
    Nature Protocols
    Volume: 12, P: 881-898