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Showing 1–9 of 9 results
Advanced filters: Author: Jan Laco Clear advanced filters

  • Live-cell imaging shows that interactions within topologically associating domains are transient and frequent throughout the cell cycle. Convergent CTCF sites regulate the frequency and duration of interactions, which last a few minutes on average.

    • Pia Mach
    • Pavel I. Kos
    • Luca Giorgetti
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 1907-1918

  • Cohesin functions must be tightly regulated. Here Prusén Mota et al. show that the cohesin regulator SORORIN is conserved beyond the animal kingdom and they provide the first organismal in vivo evidence that SORORIN antagonizes WAPL.

    • Ignacio Prusén Mota
    • Marta Galova
    • Peter Schlögelhofer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Al-Refaie et al. show that fasting induces spatial reorganization of chromatin and formation of chromatin rings in an mTORC1- and RNA Pol I-dependent manner in the C. elegans intestine.

    • Nada Al-Refaie
    • Francesco Padovani
    • Daphne S. Cabianca
    ResearchOpen Access
    Nature Cell Biology
    Volume: 26, P: 1903-1917

  • The plasmid-encoded ParMRC system is one of the best characterized plasmid segregation systems and comprises just three components: an actin-like protein, ParM, a DNA-binding adaptor protein, ParR, and a centromere-like region,parC. Here, the authors review the molecular mechanisms by which the components of this system interact to achieve bipolar DNA segregation.

    • Jeanne Salje
    • Pananghat Gayathri
    • Jan Löwe
    Reviews
    Nature Reviews Microbiology
    Volume: 8, P: 683-692

  • Forces applied to the cell surface induce stretching of the chromatin in the nucleus and a rapid increase in gene expression.

    • Tyler J. Kirby
    • Jan Lammerding
    News & Views
    Nature Materials
    Volume: 15, P: 1227-1229

  • Mechanical forces influence both cytoplasmic and nuclear events. Kirby and Lammerding discuss recent evidence suggesting that the nucleus itself is a mechanosensor and methods to study nuclear mechanotransduction.

    • Tyler J. Kirby
    • Jan Lammerding
    Reviews
    Nature Cell Biology
    Volume: 20, P: 373-381