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Showing 1–4 of 4 results
Advanced filters: Author: Janakiraman Subramanian Clear advanced filters

  • Chemotherapy options for patients with extensive-stage small-cell lung cancer (SCLC) are limited. A recent phase III trial assessed the combination of carboplatin and pemetrexed but this regimen produced inferior survival results compared with the standard carboplatin and etoposide regimen. The combination of carboplatin and etoposide remains the standard first-line chemotherapy option for the treatment of patients with extensive-stage SCLC.

    • Janakiraman Subramanian
    • Ramaswamy Govindan
    News & Views
    Nature Reviews Clinical Oncology
    Volume: 7, P: 77-78

  • A database of known drug-gene interactions, with information derived from many public sources, allows the identification of genes that are currently targeted by a drug and the membership of genes in a category, such as kinase genes, that have a high potential for drug development.

    • Malachi Griffith
    • Obi L Griffith
    • Richard K Wilson
    Research
    Nature Methods
    Volume: 10, P: 1209-1210