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Showing 1–7 of 7 results
Advanced filters: Author: Janet Ren Chao Clear advanced filters

  • Although 3D bioprinting technology has gained much attention in the field of tissue engineering, there are still several significant challenges that need to be overcome. Here, the authors present silk fibroin bioink with printability and biocompatibility suited for digital light processing 3D printing.

    • Soon Hee Kim
    • Yeung Kyu Yeon
    • Chan Hum Park
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14

  • Prostate cancer (PrCa) involves a large heritable genetic component. Here, the authors perform multivariate fine-mapping of known PrCa GWAS loci, identifying variants enriched for biological function, explaining more familial relative risk, and with potential application in clinical risk profiling.

    • Tokhir Dadaev
    • Edward J. Saunders
    • Zsofia Kote-Jarai
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-19

  • Chromosome 8q24 is known to be a major susceptibility region for prostate cancer risk. Here the authors analyze genetic data across the 8q24 region from 71,535 prostate cancer patients identifying 12 risk loci, three previously unreported, highlighting the contribution of germline variation at this locus.

    • Marco Matejcic
    • Edward J. Saunders
    • Christopher A. Haiman
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • We report methacrylated silk fibroin sealant (Sil-MAS) with rapid crosslinkable, highly adhesive and biocompatible properties and demonstrate its versatility as medical glue. The excellence for physical properties of Sil-MAS is revealed via in vitro mechanical tests and ex vivo aorta pressure test. In in vivo biological tests on skin, liver, and blood vessels of rat, Sil-MAS showed a superb hemostatic and adhesive ability with high biocompatibility. Specifically, Sil-MAS strongly contributed to fast wound healing. Furthermore, we showed that Sil-MAS could be an ideal photocuring laparoscopic medical glue in laceration rabbit model of liver and stomach serosa using self-made endoscopic device.

    • Soon Hee Kim
    • Young Jin Lee
    • Chan Hum Park
    ResearchOpen Access
    NPG Asia Materials
    Volume: 12, P: 1-16