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Showing 1–4 of 4 results
Advanced filters: Author: Jard de Vries Clear advanced filters

  • Olja Grgic, Matthew Gazzara, and Alessandra Chesi et al. perform a genome-wide association study meta-analysis for skeletal age in two pediatric cohorts. They observe that variation in the adrenal gene, CYP11B1, impacts its alternative splicing, suggesting that adrenal steroidogenesis may contribute toward variation in skeletal age in otherwise healthy children.

    • Olja Grgic
    • Matthew R. Gazzara
    • Fernando Rivadeneira
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-10

    • Joost A. M. Verlouw
    • Eva Clemens
    • Linda Broer
    ResearchOpen Access
    European Journal of Human Genetics
    Volume: 29, P: 1611-1624

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29