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Showing 1–5 of 5 results
Advanced filters: Author: Jared Cartwright Clear advanced filters

  • Stereogenic-at-sulfur compounds are important biologically active small molecules, with many drugs featuring chiral sulfur atoms. Here, the authors report that unspecific peroxygenases catalyse the biocatalytic oxygenation of sulfilimines and sulfenimines to form enantiomerically enriched sulfoximines and sulfinimines, respectively, on preparative scale.

    • Jiacheng Li
    • Benjamin Melling
    • Gideon Grogan
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-9

  • The oomycete Phytophthora infestans is a damaging crop pathogen. Here, the authors show that a group of P. infestans secreted enzymes play roles in penetration and colonization of host plants by oxidising fragments of the polysaccharide pectin in the plant cell wall.

    • Lydia R. J. Welsh
    • Anna O. Avrova
    • Federico Sabbadin
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • The genome of a western lowland gorilla has been sequenced and analysed, completing the genome sequences of all great ape genera, and providing evidence for parallel accelerated evolution in chimpanzee, gorilla and human lineages at a number of loci.

    • Aylwyn Scally
    • Julien Y. Dutheil
    • Richard Durbin
    ResearchOpen Access
    Nature
    Volume: 483, P: 169-175

  • The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

    • Richard M. Durbin
    • David Altshuler (Co-Chair)
    • Gil A. McVean
    ResearchOpen Access
    Nature
    Volume: 467, P: 1061-1073