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Showing 1–4 of 4 results

Advanced filters: Author: Jared G. Maina Clear advanced filters

Partitioned polygenic scores show mechanistic heterogeneity in type 2 diabetes and hypertension comorbidity

Type 2 diabetes and hypertension often co-occur, suggesting shared biological mechanisms. Here, Pascat et al. use partitioned polygenic scores to show distinct biological processes link both conditions and improve risk prediction.

Vincent Pascat
Liudmila Zudina
Inga Prokopenko
ResearchOpen Access09 Feb 2026
Nature Communications

Volume: 17, P: 1-14
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

Genome-wide association analyses of blood glucose measurements under nonstandardized conditions provide insights into the biology of glucose regulation, diabetes complications and pathways for treatment stratification.

Vasiliki Lagou
Longda Jiang
Cornelia M. van Duijn
ResearchOpen Access07 Sept 2023
Nature Genetics

Volume: 55, P: 1448-1461
Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results

In a prespecified 3-year analysis of the KEN SHE trial, single-dose HPV vaccination was shown to be well tolerated and provided durable protection against cervical HPV infection in Kenyan women aged 15–20 years.

Ruanne V. Barnabas
Elizabeth R. Brown
Torin T. Schaafsma
ResearchOpen Access04 Dec 2023
Nature Medicine

Volume: 29, P: 3224-3232
Abdominal obesity is a more important causal risk factor for pancreatic cancer than overall obesity

Jared G. Maina
Vincent Pascat
Inga Prokopenko
ResearchOpen Access10 May 2023
European Journal of Human Genetics

Volume: 31, P: 962-966