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Showing 1–4 of 4 results
Advanced filters: Author: Jaroslav Icha Clear advanced filters

  • Current approaches to conditionally deplete target proteins require site-specific genetic engineering or have poor temporal control. Here the authors overcome these limitations by combining the AID system with nanobodies to reversibly degrade GFP-tagged proteins in living cells and zebrafish.

    • Katrin Daniel
    • Jaroslav Icha
    • Jörg Mansfeld
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • Experiments in zebrafish and human tissues show that, during retinal morphogenesis, emerging photoreceptor cells migrate in a bidirectional manner, which lessens competition for space and helps to ensure that the retina is formed correctly.

    • Mauricio Rocha-Martins
    • Elisa Nerli
    • Caren Norden
    Research
    Nature
    Volume: 620, P: 615-624

  • Moreno-Layseca et al. discuss how integrins, key receptors that mediate cell adhesion to the extracellular matrix, are endocytosed and recycled to the cell surface to modulate cell and tissue behaviour.

    • Paulina Moreno-Layseca
    • Jaroslav Icha
    • Johanna Ivaska
    Reviews
    Nature Cell Biology
    Volume: 21, P: 122-132