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Showing 1–5 of 5 results

Advanced filters: Author: Jason Heth Clear advanced filters

A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury

Mechanisms promoting epithelial regeneration after intestinal injury are poorly understood. Here, authors report that intestinal stem cells produce IL-33 after radiation injury, which induces Paneth cells to produce EGF and promote regeneration.

Marco Calafiore
Ya-Yuan Fu
Alan M. Hanash
ResearchOpen Access05 Sept 2023
Nature Communications

Volume: 14, P: 1-13
Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy

By taking advantage of stimulated Raman spectroscopy and fibre-laser technology, virtual histology images can be obtained in real time in the operating room, with diagnostic quality comparable with that achieved via conventional histopathology.

Daniel A. Orringer
Balaji Pandian
Sandra Camelo-Piragua
Research06 Feb 2017
Nature Biomedical Engineering

Volume: 1, P: 1-13
Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging

DeepGlioma, a multimodal deep learning approach for intraoperative diagnostic screening of diffuse glioma, trained on stimulated Raman histology and large-scale public genomic data, can predict molecular alterations for diffuse glioma diagnosis with high accuracy.

Todd Hollon
Cheng Jiang
Daniel A. Orringer
Research23 Mar 2023
Nature Medicine

Volume: 29, P: 828-832
Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks

A prospective, multicenter, case–control clinical trial evaluates the potential of artificial intelligence for providing accurate bedside diagnosis of patients with brain tumors.

Todd C. Hollon
Balaji Pandian
Daniel A. Orringer
Research06 Jan 2020
Nature Medicine

Volume: 26, P: 52-58
Targeting fatty acid synthase in preclinical models of TNBC brain metastases synergizes with SN-38 and impairs invasion

Habib A. Serhan
Liwei Bao
Nathan M. Merrill
ResearchOpen Access10 Jun 2024
npj Breast Cancer

Volume: 10, P: 1-7