Nature Search

Microbial signals in primary and metastatic brain tumors

A combination of high-resolution spatial imaging, spatial proteomics and transcriptional data reveals sparse and heterogeneous bacterial signals in gliomas and brain metastases.

Golnaz Morad
Ashish V. Damania
Jennifer A. Wargo
ResearchOpen Access14 Nov 2025
Nature Medicine

Volume: 31, P: 3675-3688
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing

Microporous annealed-particle degradable scaffolds have been developed and shown to induce type 2 innate and adaptive immune response that facilitated skin wound healing.

Donald R. Griffin
Maani M. Archang
Philip O. Scumpia
Research09 Nov 2020
Nature Materials

Volume: 20, P: 560-569
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Search for topological defect dark matter with a global network of optical magnetometers

A search for transient dark matter in the form of domain walls of axion-like particles finds no statistically significant signal. This places constraints on our theoretical understanding of such scenarios.

Samer Afach
Ben C. Buchler
Jianwei Zhang
ResearchOpen Access07 Dec 2021
Nature Physics

Volume: 17, P: 1396-1401
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation

The human germinal centre-associated lymphoma gene is expressed in germinal centre B-lymphocytes; however, its function is unknown. Here the authors show that human germinal centre-associated lymphoma activates Syk kinase, leading to lymphoid hyperplasia and systemic reactive amyloid A amyloidosis in transgenic mice.

Isabel Romero-Camarero
Xiaoyu Jiang
Izidore S Lossos
Research08 Jan 2013
Nature Communications

Volume: 4, P: 1-12
The messy death of a multiple star system and the resulting planetary nebula as observed by JWST

JWST observations of the planetary nebula NGC 3132 reveal a rich molecular environment containing evidence of multiple stellar interactions on a variety of scales.

Orsola De Marco
Muhammad Akashi
Albert A. Zijlstra
Research08 Dec 2022
Nature Astronomy

Volume: 6, P: 1421-1432
HIV-1 targets L-selectin for adhesion and induces its shedding for viral release

HIV binding is mediated via CD4 and chemokine co-receptors, but this does not explain the preferential infection of central memory CD4+ T cells. Here the authors show HIV targets L-selectin, induces shedding from the infected cell, and inhibition of L-selectin reduces HIV infection and release.

Joseph Kononchik
Joanna Ireland
Peter Sun
ResearchOpen Access19 Jul 2018
Nature Communications

Volume: 9, P: 1-15
Author Correction: The messy death of a multiple star system and the resulting planetary nebula as observed by JWST

Orsola De Marco
Muhammad Akashi
Albert A. Zijlstra
Amendments and Corrections03 Jan 2023
Nature Astronomy

Volume: 7, P: 234
A resource of targeted mutant mouse lines for 5,061 genes

The International Mouse Phenotyping Consortium reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter alleles.

Marie-Christine Birling
Atsushi Yoshiki
Stephen A. Murray
Comments & Opinion08 Apr 2021
Nature Genetics

Volume: 53, P: 416-419
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Hydrogel microparticles for biomedical applications

Hydrogel microparticles are used for numerous biomedical applications, owing to their unique multiscale properties and design versatility. This Review discusses various hydrogel microparticle fabrication techniques and their diverse applications, ranging from cell and drug delivery to 3D printing.

Andrew C. Daly
Lindsay Riley
Jason A. Burdick
Reviews07 Nov 2019
Nature Reviews Materials

Volume: 5, P: 20-43
Cognitive profile, neuroimaging and fluid biomarkers in post-acute COVID-19 syndrome

Núria Guillén
Agnès Pérez-Millan
Raquel Sanchez-Valle
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-14

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