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Showing 1–10 of 10 results
Advanced filters: Author: Javier Gallego-Bartolomé Clear advanced filters

  • It has generally been considered that MOM1, a transcriptional silencing factor in plants, mediated silencing is independent or downstream of DNA methylation. Here, the authors show that MOM1 complex recruits the RdDM machinery through MORC6 to establish de novo DNA methylation in Arabidopsis.

    • Zheng Li
    • Ming Wang
    • Steven E. Jacobsen
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Plants respond to shade by elongating their stems to grow toward the light. Here, Crocco et al. show that the BBX24 transcriptional regulator promotes the shade avoidance response by activating gibberellin signalling and the PIF4 transcription factor under low light conditions.

    • Carlos D. Crocco
    • Antonella Locascio
    • Javier F. Botto
    Research
    Nature Communications
    Volume: 6, P: 1-10

  • The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of methylation.

    • Wanlu Liu
    • Javier Gallego-Bartolomé
    • Steven E. Jacobsen
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • RNA polymerase V transcription in plants, which is needed DNA methylation and transcriptional silencing, requires components of the DDR complex. Here the authors show that all components of the DDR complex co-localize with Pol V and report the cryoEM structures of two complexes associated with Pol V recruitment.

    • Somsakul Pop Wongpalee
    • Shiheng Liu
    • Steven E. Jacobsen
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Activating the expression of host susceptibility (S) genes is one of the strategies plant pathogens employed to promote infection of their host. Here, the authors show that targeted methylation at the TAL20 effector binding element of the cassava SWEET10a gene lead to resistance to Xanthomonas phaseoli.

    • Kira M. Veley
    • Kiona Elliott
    • Rebecca S. Bart
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-9

  • TRB proteins have been shown to recruit PRC2 for H3K27me3 deposition. This work shows that TRBs also recruit JMJ14 to remove H3K4me3, demonstrating that TRBs silence the target genes via a combinatorial histone modification mechanism.

    • Ming Wang
    • Zhenhui Zhong
    • Steven E. Jacobsen
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • MORC ATPases are required for transposable element silencing and heterochromatin condensation in plants and animals. Here the authors show that Arabidopsis MORCs colocalize with sites of RNA-directed DNA methylation and provide evidence that they act as molecular tethers to efficiently establish DNA methylation.

    • Yan Xue
    • Zhenhui Zhong
    • Steven E. Jacobsen
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.

    • Ashot Papikian
    • Wanlu Liu
    • Steven E. Jacobsen
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11