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Showing 1–3 of 3 results
Advanced filters: Author: Jean Albrengues Clear advanced filters

  • Interactions with the extracellular matrix (ECM) control tumor proliferation, invasion and metastasis. Here, authors provide spatial information on ECM organization and how it influences tumor cell invasive and metastasis properties through induction of cytoskeletal and transcriptional memory.

    • Oscar Maiques
    • Marta C. Sallan
    • Victoria Sanz-Moreno
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-23

  • Migrating cancer cells are round or elongated, and it is thought that the differently shaped cells invade surrounding tissue using different mechanisms. Here, Orgaz et al. show that the round cells secrete matrix metalloproteinases, which allow them to degrade surrounding connective tissue more effectively than elongated cells.

    • Jose L. Orgaz
    • Pahini Pandya
    • Victoria Sanz-Moreno
    Research
    Nature Communications
    Volume: 5, P: 1-13