Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Jean-Ju Chung Clear advanced filters

  • ARMH2 is identified as a previously unknown cytosolic component of the sperm-specific CatSper channel, critical for its normal assembly and pH/calcium sensitivity. Loss of ARMH2 impairs sperm hyperactivation and causes severe subfertility.

    • Qingqing Zhao
    • Shiyi Lin
    • Jianping Wu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • Sperm motility and male fertility requires function of the CatSper calcium channels. Here, using cryo-electron tomography, authors visualize the native in-cell 3D structure and higher-order organization of the CatSper as long zigzag rows along the sperm tail.

    • Yanhe Zhao
    • Huafeng Wang
    • Jean-Ju Chung
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • The CATSPER heteromeric ion channel complex is required for male fertility and six protein components of the complex have been identified. In this study, the authors identify a seventh gene, CATSPERδ, which is necessary for functional CatSper channels and hyperactivated sperm motility.

    • Jean-Ju Chung
    • Betsy Navarro
    • David E. Clapham
    Research
    Nature Communications
    Volume: 2, P: 1-12

  • Mammalian sperm must respond to a variety of cues, and dynamic regulation of ion signalling is, therefore, essential for sperm cells to adapt to their environment. In this Review, the authors describe the ion channels and membrane receptors controlling sperm activity, in particular the principal Ca2+-selective plasma membrane ion channel CatSper, and consider how sperm ion channels and membrane receptors are attractive targets for therapeutics and how these signalling processes might have implications for assisted reproductive technologies.

    • Huafeng Wang
    • Luke L. McGoldrick
    • Jean-Ju Chung
    Reviews
    Nature Reviews Urology
    Volume: 18, P: 46-66