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Nature Metabolism (1)

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Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

Molecular pharmacological characterization and association testing of human GIPR genetic variants with follow-up analysis in mice shows that β-arrestins regulate GIPR signalling and thereby strongly contribute to metabolic outcomes.

Hüsün S. Kizilkaya
Kimmie V. Sørensen
Mette M. Rosenkilde
ResearchOpen Access13 Jun 2024
Nature Metabolism

Volume: 6, P: 1268-1281

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Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

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