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Round-table talks aim to slow climate warming by transforming agriculture.

Geology and infrastructure could impede development.

A new generation of economists is trying to transform global development policy through the power of randomized controlled trials.

Evidence that increasing temperatures harm productivity raises questions about the effects of warming on economic growth.

Economic modelling shows that the compromise legislation might bring the United States within range of meeting its climate commitments.

More than a billion people lack electricity, but now microgrids are powering up rural areas.

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Backers hope that a network of next-generation modelling centres will help to whittle away uncertainties about the effects of global warming.

Nearly four years after US President Barack Obama pledged to put science in its rightful place, Nature asks if he kept his word.

Months after the military expelled thousands of illegal miners from La Pampa, researchers gained access to a sandy wasteland.

The daughter of a scientist and a supporter of diversity in STEM, Harris as a potential candidate has stirred optimism among scientists.

US President Barack Obama rejects pipeline to transport oil from Canada's tar sands to refineries along the Gulf of Mexico.

A movement to privatize Earth-observing satellites is gaining ground.

But government incentives go begging as applications for plants dry up.

Interactions amongst Bacillus subtilis cells in a defined spatial environment are sufficient to enable the formation of self-organized patches that allow survival at cell densities otherwise too low to sustain growth.

Company claims it will have a working reactor in a decade.

New study finds untapped shale reserves set to displace coal if carbon pricing enforced

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

With the world set to blow past its temperature targets, efforts are growing to remove greenhouse gases from the atmosphere.

Stable carbon isotope analysis of mouse organs reveals no evidence for gut microbial essential amino acid provisioning after microbiome reconstitution as demonstrated by the nearly identical isotope patterns in germ-free and conventionalized mice.

Sex differences in fasting glucose and insulin have been identified, but the genetic loci underlying these differences have not. Here, the authors perform a meta-analysis of genome-wide association studies to detect sex-specific and sex-dimorphic loci associated with fasting glucose and insulin.

Aiming for declining global temperatures can limit long-term climate risks compared with a mere stabilization of global warming, including sea-level rise and cryosphere changes.

In this Review, Jeff Shrager and Marty Tenenbaum describe the latest generation of Precision Oncology, and the different ways to keep refining it. In Precision Oncology 3.0, each treatment event provides the chance to learn from it so that such treatment can be applied to other patients with similar characteristics without facing the difficult economic and structural challenges of a clinical trial.

Proposed rules for US Environmental Protection Agency would replace Obama-era regulations to reduce carbon emissions from power plants.

The US president proposes a 2025 budget even as negotiations continue over federal funding for 2024.

Edward B. Barbier and colleagues call for governance and funds for deep-sea reserves and the restoration of ecosystems damaged by commercial interests.

Researchers are frustrated at the glacial pace of decarbonization — but cheered the commitment to create a ‘loss and damage’ fund.

A genome-wide association study and Metabochip meta-analysis of body mass index (BMI) detects 97 BMI-associated loci, of which 56 were novel, and many loci have effects on other metabolic phenotypes; pathway analyses implicate the central nervous system in obesity susceptibility and new pathways such as those related to synaptic function, energy metabolism, lipid biology and adipogenesis.

Genetic and testing data from England show that the SARS-CoV-2 variant of concern B.1.1.7 has a transmission advantage over other lineages.

Post-international travel quarantine has been widely implemented to mitigate SARS-CoV-2 transmission, but the impacts of such policies are unclear. Here, the authors used linked genomic and contact tracing data to assess the impacts of a 14-day quarantine on return to England in summer 2020.

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

Lawrence Haddad, Corinna Hawkes and colleagues propose ten ways to shift the focus from feeding people to nourishing them.

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Funding for the National Science Foundation and National Institutes of Health would hold steady after Congress agrees to lift spending caps, but details are fuzzy.

Countries have pledged to limit global warming to 2 °C, and climate models say that is still possible. But only with heroic — and unlikely — efforts.

Despite 30 years of climate diplomacy, urgent and aggressive action is needed to halt global warming. Nature explains what success looks like, and what’s on the line.

In Brazil, details are emerging for plans to stop deforestation. Can it serve as a model for other nations?

The United States has abandoned comprehensive greenhouse-gas curbs, but California is pressing ahead. Mary Nichols is leading the fight against emissions.

The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

Russia’s invasion has caused a short-term spike in prices, but could prompt a long-term shift towards sustainability.

Research models shed light on how the Build Back Better bill might reshape the US energy landscape.

Radical emissions cuts combined with some atmospheric carbon removal are the only hope to limit global warming to 1.5 °C, scientists warn.

Chances are rapidly disappearing to limit Earth’s temperature rise to the globally agreed mark, but researchers say there are some positive signs of progress.

Revoking the state’s tough fuel-efficiency standards would increase US greenhouse-gas emissions.