This study shows how somatostatin (SOM)-expressing interneurons contribute to odor coding in mouse olfactory cortex. Odor-tuned SOM cells regulate neuronal output through a purely subtractive operation that is independent of odor identity or intensity. This operation enhances the salience of odor-evoked activity without changing cortical odor tuning.
- James F Sturgill
- Jeffry S Isaacson