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Advanced filters: Author: Jennifer Dobrodziej Clear advanced filters

  • Using structural, biochemical, and functional assays, the authors demonstrate that the E3 ligase KLHDC2, via newly developed small-molecule ligands, can be co-opted to target critical targets for degradation.

    • Christopher M. Hickey
    • Katherine M. Digianantonio
    • Miklós Békés
    Research
    Nature Structural & Molecular Biology
    Volume: 31, P: 311-322