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Showing 1–3 of 3 results

Advanced filters: Author: Jens F. Kiilgaard Clear advanced filters

The genetic evolution of metastatic uveal melanoma

Multi-region sequencing of 35 primary uveal melanomas and their matched metastases yields new insights into the genetics and evolution of these tumors and provides potential biomarkers for progression and therapy.

A. Hunter Shain
Mette M. Bagger
Jens F. Kiilgaard
Research28 Jun 2019
Nature Genetics

Volume: 51, P: 1123-1130
¹⁸F-FDG PET/CT assessment of metabolic tumor burden predicts survival in patients with metastatic posterior uveal melanoma

Tine Gadegaard Hindso
Torben Martinussen
Karine Madsen
ResearchOpen Access03 Feb 2025
Scientific Reports

Volume: 15, P: 1-13
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

Uveal melanoma has a propensity to metastasise. Here, the authors report the whole genome sequence of 103 uveal melanomas and find that the tumour mutational burden is variable and that two subsets of tumours are characterised by MBD4 mutations and a UV exposure signature.

Peter A. Johansson
Kelly Brooks
Nicholas K. Hayward
ResearchOpen Access15 May 2020
Nature Communications

Volume: 11, P: 1-8