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Showing 1–2 of 2 results
Advanced filters: Author: Jeongsik Lim Clear advanced filters
  • A hybrid surface electrode array was developed, which exhibits superior signal-to-noise ratio (SNR) and outstanding conformality with the cortex surface. It was used to detect the brain signals in awake, free-moving rat models with high-throughput spatiotemporal resolution. In addition, the pilocarpine-induced epileptic discharges and behavior were considerably suppressed upon the usage of this electrode-array system. These findings pave the way for the integration of graphene into bio-medical device platforms, and their use in cranial neuropathy treatment.

    • Jeongsik Lim
    • Sangwon Lee
    • Jong-Hyun Ahn
    ResearchOpen Access
    NPG Asia Materials
    Volume: 15, P: 1-12
  • The timely and continuous measurement of cortical maps is required for studying the nature and plasticity of brain maps. In this work, we developed the multichannel graphene array that enables high-resolution brain mapping, facilitating rapid and repetitive assessments of brain maps. The advanced graphene array with intervening thru-hole enables large-scale mapping simultaneously in the surface and deep of cortical areas, also improving conformality for better detection of electrocorticography signals. In a subset of the graphene array, cortical surface stimulation can remodel cortical maps, therein enhancing cortical plasticity. This technology provides potential therapeutic applications for various brain disorders by correcting brain maps.

    • Minseok Lee
    • Sangwon Lee
    • Sungchil Yang
    ResearchOpen Access
    NPG Asia Materials
    Volume: 13, P: 1-10