Nature Search

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

Jerome Mertens
Qiu-Wen Wang
Jun Yao
Amendments and Corrections25 Nov 2015
Nature

Volume: 530, P: 242
Sterile-neutrino search based on 259 days of KATRIN data

The analysis of the energy spectrum of 36 million tritium β-decay electrons recorded in 259 measurement days within the last 40 eV below the endpoint challenges the Neutrino-4 claim.

H. Acharya
M. Aker
G. Zeller
ResearchOpen Access03 Dec 2025
Nature

Volume: 648, P: 70-75
Small molecules enable highly efficient neuronal conversion of human fibroblasts

To increase the efficiency of direct neuronal conversion of postnatal human fibroblasts, the authors combine two-factor neuronal programming with small molecules. This method increases the yield and purity of functional neuron-like cells by more than 15-fold.

Julia Ladewig
Jerome Mertens
Oliver Brüstle
Research08 Apr 2012
Nature Methods

Volume: 9, P: 575-578
Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

Cultures of human neural cells can be generated from skin cells that have been reprogrammed to produce induced pluripotent stem cells (iPSCs) or subjected to direct conversion. Gage and colleagues describe advances in differentiation protocols that allow specific subtypes of neural cell to be produced and consider the advantages and disadvantages of different approaches.

Jerome Mertens
Maria C. Marchetto
Fred H. Gage
Reviews19 May 2016
Nature Reviews Neuroscience

Volume: 17, P: 424-437
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

Using a dynamic time-course approach to model developmental trajectories in autism spectrum disorder, Schafer et al. identified aberrant gene network dynamics as a part of an ongoing process that is primed early in development.

Simon T. Schafer
Apua C. M. Paquola
Fred H. Gage
Research07 Jan 2019
Nature Neuroscience

Volume: 22, P: 243-255
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

A neuronal model of bipolar disorder based on induced pluripotent stem cell (iPSC) technology finds hyperactive action-potential firing and differential responsiveness to lithium in iPSC-derived neurons from patients with bipolar disorder.

Jerome Mertens
Qiu-Wen Wang
Jun Yao
Research28 Oct 2015
Nature

Volume: 527, P: 95-99
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

C9orf72 mutations are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia. With unbiased screens in Saccharomyces cerevisiae, Jovicic et al. identified potent modifiers of toxicity of dipeptide repeat proteins produced by unconventional translation of the C9orf72 repeat expansions, pointing to nucleocytoplasmic transport impairments as potential disease mechanisms.

Ana Jovičić
Jerome Mertens
Aaron D Gitler
Research26 Aug 2015
Nature Neuroscience

Volume: 18, P: 1226-1229
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease

Human neurons derived from induced pluripotent stem cells permit the study of aberrant protein processing and aggregation in Machado–Joseph disease.

Philipp Koch
Peter Breuer
Oliver Brüstle
Research23 Nov 2011
Nature

Volume: 480, P: 543-546
A new member of the ETS family fused to EWS in Ewing tumors

Martine Peter
Jérome Couturier
Olivier Delattre
Research13 Mar 1997
Oncogene

Volume: 14, P: 1159-1164
Cellular reprogramming as a tool to model human aging in a dish

The development of human cellular models of aging that surpass the limitations of animal models of aging is urgent. Here, the authors explore the opportunities and limitations of cellular reprogramming to create reliable aging in vitro models and their potential for the discovery of anti-aging compounds.

Patricia R. Pitrez
Luis M. Monteiro
Lino Ferreira
ReviewsOpen Access28 Feb 2024
Nature Communications

Volume: 15, P: 1-11
Towards quantitative assessment of cerebrovascular autoregulation in human neonates using ultrafast ultrasound imaging

Nikan Fakhari
Julien Aguet
Olivier Villemain
ResearchOpen Access11 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Neural cell state shifts and fate loss in ageing and age-related diseases

Here, the authors offer their perspective on the roles of cell states in sustaining health and counteracting disease, and examine how cellular ageing might set the stage for pathological fate loss and neurodegeneration.

Larissa Traxler
Raffaella Lucciola
Fred H. Gage
Reviews02 Jun 2023
Nature Reviews Neurology

Volume: 19, P: 434-443
Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia

Angeliki Spathopoulou
Gabriella A. Sauerwein
Frank Edenhofer
ResearchOpen Access29 Apr 2024
Molecular Psychiatry

Volume: 29, P: 3128-3140
The brain of fetuses with congenital diaphragmatic hernia shows signs of hypoxic injury with loss of progenitor cells, neurons, and oligodendrocytes

George Biouss
Lina Antounians
Augusto Zani
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-15
A guide for assessment of myocardial stiffness in health and disease

This Review discusses the physical concepts and descriptions of the structures that determine myocardial stiffness, different techniques used to estimate myocardial stiffness, and their application in clinical medicine.

José Carlos Villalobos Lizardi
Jerome Baranger
Olivier Villemain
Reviews12 Jan 2022
Nature Cardiovascular Research

Volume: 1, P: 8-22
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons

Mark van den Hurk
Shong Lau
Cedric Bardy
ResearchOpen Access18 Oct 2022
npj Parkinson's Disease

Volume: 8, P: 1-18
Properties and role of interfaces in multimaterial 3D printed composites

Laura Zorzetto
Luca Andena
Davide Ruffoni
ResearchOpen Access17 Dec 2020
Scientific Reports

Volume: 10, P: 1-17
Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71

Sibylle Mitschka
Thomas Ulas
Waldemar Kolanus
ResearchOpen Access09 Jun 2015
Scientific Reports

Volume: 5, P: 1-21

Search

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

Sterile-neutrino search based on 259 days of KATRIN data

Small molecules enable highly efficient neuronal conversion of human fibroblasts

Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease

A new member of the ETS family fused to EWS in Ewing tumors

Cellular reprogramming as a tool to model human aging in a dish

Towards quantitative assessment of cerebrovascular autoregulation in human neonates using ultrafast ultrasound imaging

Neural cell state shifts and fate loss in ageing and age-related diseases

Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia

The brain of fetuses with congenital diaphragmatic hernia shows signs of hypoxic injury with loss of progenitor cells, neurons, and oligodendrocytes

A guide for assessment of myocardial stiffness in health and disease

Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons

Properties and role of interfaces in multimaterial 3D printed composites

Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71

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