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Showing 1–6 of 6 results
Advanced filters: Author: Jesse R. Raab Clear advanced filters
  • Due to the pulsed nature of X-ray free electron laser (XFEL) instruments the majority of protein crystals, which are injected using continuous jet injection techniques are wasted. Here, the authors present a microfluidic device to deliver aqueous protein crystal laden droplets segmented with an immiscible oil and demonstrate that with this device an approx. 60% reduction in sample waste was achieved for data collection of 3-deoxy-D-manno-octulosonate 8-phosphate synthase crystals at the EuXFEL.

    • Austin Echelmeier
    • Jorvani Cruz Villarreal
    • Alexandra Ros
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10
  • Increasing evidence suggests functional similarities between promoters and insulators. The authors propose that these findings unify existing models of insulator function, provide new directions for understanding how insulators work and suggest that insulators have evolved from promoters.

    • Jesse R. Raab
    • Rohinton T. Kamakaka
    Reviews
    Nature Reviews Genetics
    Volume: 11, P: 439-446
  • The long noncoding RNA SCHLAP1 has been reported to act by depleting the SWI/SNF complex from genomic sites, but new data show that SWI/SNF remains localized to chromatin in the presence of SCHLAP1, suggesting that SCHLAP1 may act independently of SWI/SNF.

    • Jesse R. Raab
    • Keriayn N. Smith
    • Terry Magnuson
    Research
    Nature Genetics
    Volume: 51, P: 26-29
  • Squeezed states of light have been experimentally demonstrated to improve the performance of the Laser Interferometer Gravitational-wave Observatory (LIGO) in astrophysically relevant frequency regions. This enhanced performance may help to reach the sensitivity required for detecting gravitational waves.

    • J. Aasi
    • J. Abadie
    • J. Zweizig
    Research
    Nature Photonics
    Volume: 7, P: 613-619