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Showing 1–5 of 5 results
Advanced filters: Author: Jesse Tordoff Clear advanced filters

  • Ochre, a strain of Escherichia coli engineered to have a single stop codon, enables reassignment of four codons for non-degenerate functions, such as incorporation of non-standard amino acids into proteins.

    • Michael W. Grome
    • Michael T. A. Nguyen
    • Farren J. Isaacs
    ResearchOpen Access
    Nature
    Volume: 639, P: 512-521

  • Synthetic genetic circuits can induce cells to form simple 3D structures reminiscent of those generated during early embryonic development. This advance will help engineers build tissues that have desirable structures.

    • Jesse Tordoff
    • Ron Weiss
    News & Views
    Nature
    Volume: 559, P: 184-185

  • Caliendo and Vitu et al. developed a platform for endogenous gene expression monitoring and conditional actuator activation, by integrating noncoding RNAs downstream of the polyadenylation signal without altering endogenous gene coding sequences.

    • Fabio Caliendo
    • Elvira Vitu
    • Ron Weiss
    Research
    Nature Chemical Biology
    Volume: 21, P: 348-359

  • Richard Lifton and colleagues report a genomic analysis of cutaneous T cell lymphoma (CTCL). Their results implicate several pathways in CTCL pathogenesis, including genes involved in T cell activation and apoptosis, NF-κB signaling, chromatin remodeling and DNA damage response.

    • Jaehyuk Choi
    • Gerald Goh
    • Richard P Lifton
    Research
    Nature Genetics
    Volume: 47, P: 1011-1019