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Showing 1–2 of 2 results
Advanced filters: Author: Jessica Furlott Clear advanced filters

  • A gene therapy method using AAV can help deliver HIV-fighting antibodies long-term, but the body often rejects them. Here the authors show that a short course of the drug rapamycin helps prevent host anti-drug antibody responses, showing successful antibody delivery in mice and monkeys.

    • Sebastian P. Fuchs
    • Paula G. Mondragon
    • Ronald C. Desrosiers
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • Indian rhesus macaques are vaccinated with simian immunodeficiency virus (SIV)-restricted CD8+ T-cell epitopes, and these vaccinated animals are shown to mediate elite control of virus replication.

    • Philip A. Mudd
    • Mauricio A. Martins
    • David I. Watkins
    Research
    Nature
    Volume: 491, P: 129-133