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Showing 1–5 of 5 results
Advanced filters: Author: Jessica Gloe Clear advanced filters

  • A high-resolution transcriptomic and epigenomic cell-type atlas of the developing mouse visual cortex from embryonic to postnatal development is presented, providing a real-time dynamic molecular map associated with individual cell types and specific developmental events.

    • Yuan Gao
    • Cindy T. J. van Velthoven
    • Hongkui Zeng
    ResearchOpen Access
    Nature
    Volume: 647, P: 127-142

  • Long-distance migration and dispersion is a common characteristic of nearly all classes of telencephalic GABAergic neurons, which diversify extensively after birth in the cortex and striatum, but show limited postnatal changes in the septum, preoptic area and pallidum.

    • Cindy T. J. van Velthoven
    • Yuan Gao
    • Hongkui Zeng
    ResearchOpen Access
    Nature
    Volume: 647, P: 143-156

  •  A transcriptomic cell-type atlas of the whole adult mouse brain with ~5,300 clusters built from single-cell and spatial transcriptomic datasets with more than eight million cells reveals remarkable cell type diversity across the brain and unique cell type characteristics of different brain regions. 

    • Zizhen Yao
    • Cindy T. J. van Velthoven
    • Hongkui Zeng
    ResearchOpen Access
    Nature
    Volume: 624, P: 317-332

  • A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into functional changes and the interaction of ageing and disease.

    • Kelly Jin
    • Zizhen Yao
    • Hongkui Zeng
    ResearchOpen Access
    Nature
    Volume: 638, P: 182-196

  • The affected cellular populations during Alzheimer’s disease progression remain understudied. Here the authors use a cohort of 84 donors, quantitative neuropathology and multimodal datasets from the BRAIN Initiative. Their pseudoprogression analysis revealed two disease phases.

    • Mariano I. Gabitto
    • Kyle J. Travaglini
    • Ed S. Lein
    ResearchOpen Access
    Nature Neuroscience
    Volume: 27, P: 2366-2383