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Molecular Psychiatry (3)
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Showing 1–6 of 6 results

Advanced filters: Author: Jessica Gracias Clear advanced filters

Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia

Schizophrenia risk has been associated with the complement component 4 (C4) genes. Here the authors show that C4A is elevated in individuals with schizophrenia.

Jessica Gracias
Funda Orhan
Carl M. Sellgren
ResearchOpen Access03 Nov 2022
Nature Communications

Volume: 13, P: 1-13
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning

Postmortem studies indicate reduced synaptic density in schizophrenia. Sellgren et al. show increased synaptic pruning in patient-derived cell models and provide evidence that C4 risk variants increase engulfment, while minocycline decreases it.

Carl M. Sellgren
Jessica Gracias
Roy H. Perlis
Research04 Feb 2019
Nature Neuroscience

Volume: 22, P: 374-385
Correction: GRK3 deficiency elicits brain immune activation and psychosis

Carl M. Sellgren
Sophie Imbeault
Sophie Erhardt
Amendments and Corrections08 Nov 2021
Molecular Psychiatry

Volume: 27, P: 1855
GRK3 deficiency elicits brain immune activation and psychosis

Carl M. Sellgren
Sophie Imbeault
Sophie Erhardt
ResearchOpen Access12 May 2021
Molecular Psychiatry

Volume: 26, P: 6820-6832
Peripheral and central levels of kynurenic acid in bipolar disorder subjects and healthy controls

Carl M. Sellgren
Jessica Gracias
Sophie Erhardt
ResearchOpen Access29 Jan 2019
Translational Psychiatry

Volume: 9, P: 1-9
SARS-CoV-2 promotes microglial synapse elimination in human brain organoids

Samudyata
Ana O. Oliveira
Carl M. Sellgren
ResearchOpen Access05 Oct 2022
Molecular Psychiatry

Volume: 27, P: 3939-3950