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Advanced filters: Author: Jessica K. Mountford Clear advanced filters

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function

The lipid kinase PI3KC2α is essential for embryogenesis, yet its role in adult homeostasis is unknown. Here, the authors show that PI3KC2α regulates the structure of the internal membrane reserves of murine megakaryocytes and platelets, affecting the platelets’ adhesiveness and prothrombotic function.

Jessica K. Mountford
Claire Petitjean
Shaun P. Jackson
Research17 Mar 2015
Nature Communications

Volume: 6, P: 1-14
A meta-analysis of genetic effects associated with neurodevelopmental disorders and co-occurring conditions

This meta-analysis examines how genetic variation is associated with neurodevelopmental disorders, their overlap and their co-occurrence with disruptive, impulse control and conduct disorders.

Agnieszka Gidziela
Yasmin I. Ahmadzadeh
Margherita Malanchini
ResearchOpen Access20 Feb 2023
Nature Human Behaviour

Volume: 7, P: 642-656
Genetic neurodevelopmental clustering and dyslexia

Austeja Ciulkinyte
Hayley S. Mountford
Michelle Luciano
ResearchOpen Access15 Jul 2024
Molecular Psychiatry

Volume: 30, P: 140-150

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