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Showing 51–57 of 57 results
Advanced filters: Author: Jessica W. T. Leung Clear advanced filters
  • Semnani-Azad et al. review the evidence on prognostic factors that predict cardiovascular disease and type 2 diabetes for women, and cardiometabolic profile in offspring subsequent to gestational diabetes. The evidence was of low quality, but some maternal characteristics were predictive of unfavourable outcomes in women and their offspring.

    • Zhila Semnani-Azad
    • Romy Gaillard
    • Wei Perng
    ResearchOpen Access
    Communications Medicine
    Volume: 4, P: 1-14
  • Murphy, Kevin, Pollin et al. perform a systematic review of the evidence on the criteria used to select individuals with diabetes for genetic testing and of the evidence for the optimal methods for variant detection in genes involved in monogenic diabetes. Based on the findings the authors make recommendations and highlight challenges for the field.

    • Rinki Murphy
    • Kevin Colclough
    • Anna L. Gloyn
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-24
  • Francis et al. perform a systematic review and meta-analysis to evaluate studies comparing perinatal outcomes among individuals with gestational diabetes mellitus (GDM). Their review and post hoc analysis find that maternal preconception weight and non-glucose-dependent biochemical markers could be a precision diagnostic approach to reducing variability in clinical outcomes following treatment.

    • Ellen C. Francis
    • Camille E. Powe
    • Paul W. Franks
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-17
  • Felton et al. conducted a systematic review to evaluate studies testing disease-modifying therapies and features linked to treatment response for type 1 diabetes prevention. While the quality of prevention and intervention trials is found to be high, precision analyses on factors associated with treatment response are of poorer quality.

    • Jamie L. Felton
    • Kurt J. Griffin
    • Paul W. Franks
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-16
  • Semple et al. review the literature to assess the effects of pharmacologic or surgical interventions in monogenic insulin resistance when stratified by genotype. The evidence guiding genotype-specific treatment of monogenic insulin resistance is of low to very low quality, but suggestive of benefits of metreleptin, thiazolidinediones, and rhIGF-1.

    • Robert K. Semple
    • Kashyap A. Patel
    • Rebecca J. Brown
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-11
  • Benham, Gingras, McLennan, Most, Yamamoto, Aiken et al. conduct two systematic reviews and meta-analyses to evaluate whether a precision-based medicine approach can be adopted to improve the clinical management of gestational diabetes (GDM). They find some precision markers that may improve the treatment course of GDM but further research is needed.

    • Jamie L. Benham
    • Véronique Gingras
    • Paul W. Franks
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-13