The Gabija system constitutes one of the most prevalent anti-phage defense systems and is composed of GajA and GajB. Here, using cryo-EM and biochemistry, the authors show that GajA and GajB form a supramolecular complex with a stoichiometry of 4:4 to promote anti-phage defense.
- Xiao-Yuan Yang
- Zhangfei Shen
- Tian-Min Fu