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Showing 1–50 of 57 results

Advanced filters: Author: Jianfang Liu Clear advanced filters

Facile hermetic TEM grid preparation for molecular imaging of hydrated biological samples at room temperature

Electron microscopy of native hydrated biological samples close to physiological temperature is challenging. Here, authors encapsulate proteins and cells as an efficient, cost-effective complement to other microscopy technique in addressing biological questions at the molecular level.

Lingli Kong
Jianfang Liu
Gang Ren
ResearchOpen Access13 Sept 2023
Nature Communications

Volume: 14, P: 1-10
Enhanced PAM50 subtyping of breast cancer implemented in the PCAPAM50 R package

Praveen-Kumar Raj-Kumar
Boyi Chen
Hai Hu
ResearchOpen Access13 Dec 2025
Scientific Reports

Volume: 16, P: 1-9
Author Correction: Tumor-specific memory CD8⁺ T cells are strictly resident in draining lymph nodes during tumorigenesis

Qiao Liu
Ling Ran
Qizhao Huang
Amendments and CorrectionsOpen Access25 May 2023
Cellular & Molecular Immunology

Volume: 20, P: 858
Mesh-like structure integrated core-shell-shell nanocomposites for enhanced stability and performance in carbon capture

The study reports a metal-organic framework (MOF) - covalent organic framework (COF) nanocomposite with dual amine sites that captures CO₂ efficiently and remains stable under humid, harsh conditions, offering a promising path for next-generation carbon capture.

Sizhuo Yang
Haiyan Mao
Jeffrey J. Urban
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-11
High-fidelity topochemical polymerization in single crystals, polycrystals, and solution aggregates

Topochemical polymerization (TCP) emerges as a leading approach for synthesizing single crystalline polymers, but the untapped potential of performing TCP in a liquid medium with solid-state structural fidelity presents unsolved challenges. Here, the authors reveal details of single-crystal-to-single-crystal transformation during the TCP of chiral azaquinodimethane monomers through in situ crystallographic analysis while spotlighting a rare metastable crystalline phase.

Chongqing Yang
Jianfang Liu
Yi Liu
ResearchOpen Access12 Apr 2025
Nature Communications

Volume: 16, P: 1-10
GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection

Metabolic dysfunction is an important characteristic of vascular smooth muscle cells (VSMCs) phenotypic transition in aortic dissection. Here, the authors show lncRNA H19 could encode a peptide, GMRSP. GMRSP regulates the glycolysis by counteracting hnRNP A2B1-mediated pyruvate kinase M pre-mRNA alternative splicing and control the phenotypic transition of VSMCs.

Jizhong Wang
Jitao Liu
Jianfang Luo
ResearchOpen Access18 Feb 2025
Nature Communications

Volume: 16, P: 1-19
Food safety incidents in Beijing: occurrence patterns, causes and wider social implications

Feiyan Liu
Yang Liu
Jianfang Zhang
ResearchOpen Access06 Oct 2015
Palgrave Communications

Volume: 1, P: 1-7
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may have a role in disease aetiology.

Fang Qiu
Ruqi Tang
Xiong Ma
ResearchOpen Access20 Apr 2017
Nature Communications

Volume: 8, P: 1-8
A pollen selection system links self and interspecific incompatibility in the Brassicaceae

Through genetic and molecular analyses of interspecific stigma–pollen interactions, the authors show that Brassicaceae plants use an integrated pollen discrimination system and a shared pollen rejection pathway to reject conspecific self-pollen and heterospecific pollen. This establishes a mechanistic link between self-incompatibility and speciation in this clade.

Bo Liu
Mengya Li
Pei Liu
Research18 Apr 2024
Nature Ecology & Evolution

Volume: 8, P: 1129-1139
D-orbital Reconstruction Achieves Low Charge Overpotential in Li-oxygen Batteries

Achieving low charge overpotential in Li-O₂ batteries is critical yet highly challenging. Here, the authors report an orbital reconstruction strategy to enhance the oxygen evolution reaction kinetics by employing PdCo nanosheets, improving charge kinetics and energy conversion efficiency.

Yin Zhou
Kun Yin
Guo Hong
ResearchOpen Access09 Apr 2025
Nature Communications

Volume: 16, P: 1-9
Integrative residue-intuitive machine learning and MD Approach to Unveil Allosteric Site and Mechanism for β2AR

The identification of cryptic allosteric sites presents a formidable challenge. Here, the authors develop a residue-intuitive hybrid ML model coupled with MD simulation to successfully identify a novel allosteric site of β2AR and a negative allosteric modulator.

Xin Chen
Kexin Wang
Xuemei Pu
ResearchOpen Access16 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Identification of driving factors and water quality evaluation of groundwater in Quanzhou City, a typical coastal area in Southeast China

Guowei Shi
Jianfang Dong
Yasong Li
ResearchOpen Access13 Nov 2025
Scientific Reports

Volume: 15, P: 1-16
PARG inhibition suppresses breast cancer progression and potentiates immunoresponse through MTDH degradation mediated by E3 ligase ITCH-dependent ubiquitination

Junnai Wang
Yanhua Dong
Lei Li
ResearchOpen Access18 Dec 2025
npj Breast Cancer

Volume: 11, P: 1-13
Designed and biologically active protein lattices

Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function.

Shih-Ting Wang
Brian Minevich
Oleg Gang
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-11
Non-averaged single-molecule tertiary structures reveal RNA self-folding through individual-particle cryo-electron tomography

Using cryogenic electron tomography (cryo-ET) and individual-particle cryo-electron tomography (IPET), non-averaged ternary structures of individual RNA origami 6HBC particles were determined, allowing observation of structural diversity and self-folding dynamics during the maturation process after transcription.

Jianfang Liu
Ewan K. S. McRae
Gang Ren
ResearchOpen Access21 Oct 2024
Nature Communications

Volume: 15, P: 1-18
Plasmonic gold mushroom arrays with refractive index sensing figures of merit approaching the theoretical limit

Plasmonic resonances in nanostructures are useful for high-performance biosensors. Shen et al. build arrays of nanoscale gold mushrooms with a high figure of merit close to the predicted upper limit and show their use for detecting low concentrations of cytochrome cand alpha-fetoprotein.

Yang Shen
Jianhua Zhou
Jianfang Wang
Research27 Aug 2013
Nature Communications

Volume: 4, P: 1-9
Angle between DNA linker and nucleosome core particle regulates array compaction revealed by individual-particle cryo-electron tomography

Here, using cryo-ET, the 3D structures of individual nucleosome particles were characterized to observe changes under varying ionic strengths and in the presence of protein H1, revealing key regulatory roles in chromatin organization dynamics.

Meng Zhang
César Díaz-Celis
Gang Ren
ResearchOpen Access23 May 2024
Nature Communications

Volume: 15, P: 1-16
Zero-sample mural superresolution reconstruction for enhanced perceptual quality

Jianfang Cao
Xiaohui Hu
Yun Tian
ResearchOpen Access04 Apr 2023
Heritage Science

Volume: 11, P: 1-9
Interfacial engineering of Bi₂S₃/Ti₃C₂T_x MXene based on work function for rapid photo-excited bacteria-killing

MXenes have emerged as potential antimicrobial materials. Here, the authors report on the creation of a Schottky junction to increase the charge separation between MXenes and semiconductor to increase photodynamic creation of reactive oxygen species under near infrared irradiation for antibacterial purposes.

Jianfang Li
Zhaoyang Li
Shuilin Wu
ResearchOpen Access22 Feb 2021
Nature Communications

Volume: 12, P: 1-10
Proteogenomic characterization of invasive breast tumors in young women

Praveen-Kumar Raj-Kumar
Jianfang Liu
Hai Hu
ResearchOpen Access18 Aug 2025
npj Breast Cancer

Volume: 11, P: 1-19
Direct in situ measurements of electrical properties of solid–electrolyte interphase on lithium metal anodes

The solid–electrolyte interphase is widely viewed as key to governing the performance of rechargeable batteries, but its electrical properties remain elusive. Here the authors develop an experimental approach to directly measure the properties and show that the solid–electrolyte interphase has a voltage-dependent conducting behaviour.

Yaobin Xu
Hao Jia
Chongmin Wang
Research28 Sept 2023
Nature Energy

Volume: 8, P: 1345-1354
Structure, folding and flexibility of co-transcriptional RNA origami

RNA nanostructures can be designed to fold during transcription, but the solution structure has remained elusive. Here the authors use cryogenic electron microscopy to determine the structure of a panel of RNA origami shapes and uncover the design and folding principles.

Ewan K. S. McRae
Helena Østergaard Rasmussen
Ebbe Sloth Andersen
Research27 Feb 2023
Nature Nanotechnology

Volume: 18, P: 808-817
Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19

Xiangyu Chen
Zhiwei Pan
Lilin Ye
ResearchOpen Access02 Sept 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-6
Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus

Avian strains of the influenza virus sometimes infect human hosts with severe consequences. Here, Wang et al.report that the H10N8 avian influenza virus, for which two lethal human infections have been reported, possesses restricted affinity towards the human receptor and suggest a structural basis for H10N8’s limited virulence.

Min Wang
Wei Zhang
George F. Gao
Research09 Jan 2015
Nature Communications

Volume: 6, P: 1-7
Biological features of novel avian influenza A (H7N9) virus

An initial characterization of the receptor-binding properties of the novel avian influenza A (H7N9) shows that the virus has acquired the ability to bind human receptors while retaining the ability to bind avian receptors; the virus infects epithelial cells in the human lower respiratory tract and type II pneumocytes in the alveoli, and hypercytokinaemia was seen in infected patients.

Jianfang Zhou
Dayan Wang
Yuelong Shu
Research03 Jul 2013
Nature

Volume: 499, P: 500-503
Open-channel metal particle superlattices

DNA-mediated assembly of hollow nanoparticles can be used in an edge-bonding approach to design and synthesize nanoscale open-channel superlattices, with control of symmetry, geometry and topology.

Yuanwei Li
Wenjie Zhou
Chad A. Mirkin
Research26 Oct 2022
Nature

Volume: 611, P: 695-701
Algae explosive growth mechanism enabling weather-like forecast of harmful algal blooms

Rongxiang Tian
Jianfang Chen
Huanxin Weng
ResearchOpen Access02 Jul 2018
Scientific Reports

Volume: 8, P: 1-7
Genetic Diversity of Avian Influenza A (H10N8) Virus in Live Poultry Markets and Its Association with Human Infections in China

Mingbin Liu
Xiaodan Li
Yuelong Shu
ResearchOpen Access15 Jan 2015
Scientific Reports

Volume: 5, P: 1-8
Terahertz beat oscillation of plasmonic electrons interacting with femtosecond light pulses

Xinping Zhang
Jianfang He
Feifei Liu
ResearchOpen Access06 Jan 2016
Scientific Reports

Volume: 6, P: 1-8
Three-dimensional structural dynamics of DNA origami Bennett linkages using individual-particle electron tomography

Scaffolded DNA origami by folding single-stranded DNA into three-dimensional nanostructures holds promise for building functional nanomachines, yet their dynamic structures remain largely unknown. Here, Lei et al. address this issue using individual-particle electron tomography at 6–14 nm resolution.

Dongsheng Lei
Alexander E. Marras
Gang Ren
ResearchOpen Access09 Feb 2018
Nature Communications

Volume: 9, P: 1-8
Chromosome-level genome assembly of Qihe gibel carp

Kaiqi Lian
Jinyan Shan
Renhai Peng
ResearchOpen Access24 Jul 2025
Scientific Data

Volume: 12, P: 1-8
Chemical insights into pottery production and use at Neolithic Zoumaling earthen-walled town in China

Jianfang Wu
Xinyue Ao
Tao Li
ResearchOpen Access19 Apr 2025
npj Heritage Science

Volume: 13, P: 1-12
VASN drives gastric tumorigenesis via activation of the COL4A1/PI3K/AKT axis during Helicobacter pylori infection

Rulin Zhao
Jun Xie
Yong Xie
Research23 Jun 2025
British Journal of Cancer

Volume: 133, P: 473-485
Effects of Chinese Medicine as Adjunct Medication for Adjuvant Chemotherapy Treatments of Non-Small Cell Lung Cancer Patients

Lijing Jiao
Changsheng Dong
Ling Xu
ResearchOpen Access24 Apr 2017
Scientific Reports

Volume: 7, P: 1-12
Individualized therapy guided by single-cell sequencing in anti-GABA_AR encephalitis

Yaqing Shu
Yu Huang
Wei Qiu
ResearchOpen Access08 Mar 2025
Translational Psychiatry

Volume: 15, P: 1-8
Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses

Jian He
Jing Yan
Rui Yue
ResearchOpen Access20 Jan 2021
Cell Research

Volume: 31, P: 742-757
Restoration of an ancient temple mural by a local search algorithm of an adaptive sample block

Jianfang Cao
Yanfei Li
Hongyan Cui
ResearchOpen Access18 Jun 2019
Heritage Science

Volume: 7, P: 1-14
Improved region growing algorithm for the calibration of flaking deterioration in ancient temple murals

Jianfang Cao
Yanfei Li
Qi Zhang
ResearchOpen Access27 Nov 2018
Heritage Science

Volume: 6, P: 1-12
An alternating multiple residual Wasserstein regularization model for Gaussian image denoising

Ruiqiang He
Wangsen Lan
Fang Liu
ResearchOpen Access25 Nov 2024
Scientific Reports

Volume: 14, P: 1-18
Lysosomal enzyme binding to the cation-independent mannose 6-phosphate receptor is regulated allosterically by insulin-like growth factor 2

Richard N. Bohnsack
Sandeep K. Misra
Nancy M. Dahms
ResearchOpen Access06 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
PHF10 inhibits gastric epithelium differentiation and induces gastric cancer carcinogenesis

Zhiyuan Fan
Wenjing Yan
Beiqin Yu
ResearchOpen Access10 Aug 2024
Cancer Gene Therapy

Volume: 31, P: 1511-1524
Improved Bioavailability and Antitumor Effect of Docetaxel by TPGS Modified Proniosomes: In Vitro and In Vivo Evaluations

Helong Liu
Liangxing Tu
Kaili Hu
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-11
PIK3C2A is a gene-specific target of microRNA-518a-5p in imatinib mesylate-resistant gastrointestinal stromal tumor

Yuan Shi
Xiaodong Gao
Yingyong Hou
Research07 Mar 2016
Laboratory Investigation

Volume: 96, P: 652-660
Single-Molecule 3D Images of “Hole-Hole” IgG1 Homodimers by Individual-Particle Electron Tomography

Dongsheng Lei
Jianfang Liu
Gang Ren
ResearchOpen Access20 Jun 2019
Scientific Reports

Volume: 9, P: 1-15
Ancient mural restoration based on a modified generative adversarial network

Jianfang Cao
Zibang Zhang
Qi Zhang
ResearchOpen Access29 Jan 2020
Heritage Science

Volume: 8, P: 1-14
Mural classification model based on high- and low-level vision fusion

Jianfang Cao
Hongyan Cui
Aidi Zhao
ResearchOpen Access24 Nov 2020
Heritage Science

Volume: 8, P: 1-18
Dual role of carcinoembryonic antigen-related cell adhesion molecule 6 expression in predicting the overall survival of gastric cancer patients

Mingde Zang
Lei Hu
Bingya Liu
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-11
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes

Qiong Yuan
Yunwei Sun
Chunxiang Zhang
ResearchOpen Access08 Mar 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-12
The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection

Xiangyu Chen
Guoshuai Cao
Lilin Ye
ResearchOpen Access06 Mar 2019
Cellular & Molecular Immunology

Volume: 17, P: 247-260
The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

Leiqiong Gao
Jing Zhou
Lilin Ye
ResearchOpen Access08 Mar 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-10

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