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Proximal proteomics reveals a landscape of human nuclear condensates

Li, Li, Wu et al. use a proteomics approach, PhastID to identify protein components of nuclear condensates (NCs). They reveal crosstalk between NCs, the dynamics of condensate components and identify an NC formed by BUD13.

Ruofei Li
Yingying Li
Feng Liu
Research28 Nov 2025
Nature Cell Biology

Volume: 27, P: 2198-2213
RSGPT: a generative transformer model for retrosynthesis planning pre-trained on ten billion datapoints

Computer-aided synthesis-planning methods have significantly assisted synthesis planning. In this work, the authors present RSGPT, a generative model pre-trained on ten billion data points, achieving state-of-the-art performance for synthesis planning

Yafeng Deng
Xinda Zhao
Xiaojian Wang
ResearchOpen Access31 Jul 2025
Nature Communications

Volume: 16, P: 1-14
p38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression

Dendritic cell-based approaches to induce antitumour immunity are promising, but have not shown encouraging results in clinical trials. Here the authors show that inhibition of p38 MAPK in dendritic cells increases expression of OX40L, boosting antitumour T-cell responses and dampening regulatory T-cell activity.

Yong Lu
Mingjun Zhang
Qing Yi
Research24 Jun 2014
Nature Communications

Volume: 5, P: 1-14
Serum calcium is associated with sudden cardiac arrest in stroke patients from ICU: a multicenter retrospective study based on the eICU collaborative research database

Jianfei Hou
Zhenhua Huang
Lingna Zhang
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-10
Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array

Qing Ma
Xuexue Liu
Lin Jiang
ResearchOpen Access19 Apr 2017
Scientific Reports

Volume: 7, P: 1-10

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Proximal proteomics reveals a landscape of human nuclear condensates

RSGPT: a generative transformer model for retrosynthesis planning pre-trained on ten billion datapoints

p38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression

Serum calcium is associated with sudden cardiac arrest in stroke patients from ICU: a multicenter retrospective study based on the eICU collaborative research database

Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array

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