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Cell Death Discovery (1)
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PRPS2 enhances RNA m⁶A methylation by stimulating SAM synthesis through enzyme-dependent and independent mechanisms

Cancer cells exploit altered metabolic pathways to dynamically regulate epigenetic methylations. Here, the authors show the canonical metabolic and nonmetabolic functions of PRPS2 in enhancing ATP utilization and SAM biosynthesis, promoting RNA m⁶A methylation for lung tumorigenesis and metastasis.

Lin Zhang
Xian Zhao
Liang Zhang
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-15
RMI1 facilitates repair of ionizing radiation–induced DNA damage and maintenance of genomic stability

Lianying Fang
Yuxiao Sun
Chang Xu
ResearchOpen Access25 Nov 2023
Cell Death Discovery

Volume: 9, P: 1-11
Understanding climate change impacts on drought in China over the 21st century: a multi-model assessment from CMIP6

Feng Xu
Yanping Qu
Qianfeng Wang
ResearchOpen Access30 Jan 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-12

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