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SARS-CoV-2 spike-specific nasal-resident CD49a⁺CD8⁺ memory T cells exert immediate effector functions with enhanced IFN-γ production

For infections that affect peripheral tissues it is better to promote immune responses in these tissues. Here the authors characterise nasal mucosal SARS-CoV-2-specific T cells in vaccinated individuals with or without breakthrough infection and show persistence and immediate effector function of these cells.

Min-Seok Rha
Gyeongyeob Kim
Eui-Cheol Shin
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-12
Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

How NMDAR and GABA neuronal dysfunctions result in impaired social behaviour is unclear. Here, the authors show that NMDARs and gap junctions in cortical PV interneurons modulate burst firing, affecting social behaviour.

Eunee Lee
Seungjoon Lee
Eunjoon Kim
ResearchOpen Access25 Aug 2021
Nature Communications

Volume: 12, P: 1-20
In vivo magnetogenetics for cell-type-specific targeting and modulation of brain circuits

Minimally invasive cellular-level target-specific neuromodulation is needed to decipher brain function and neural circuitry. Here nano-magnetogenetics using magnetic force actuating nanoparticles has been reported, enabling wireless and remote stimulation of targeted deep brain neurons in freely behaving animals.

Seo-Hyun Choi
Jihye Shin
Jinwoo Cheon
Research02 Jul 2024
Nature Nanotechnology

Volume: 19, P: 1333-1343
FDA-approved phensuximide inhibits RIPK1-dependent immunogenic cell death

Byeong-Ju Kim
Sun Mi Hong
You-Sun Kim
ResearchOpen Access02 Jun 2025
Cell Death & Disease

Volume: 16, P: 1-15
Refining microbiome diversity analysis by concatenating and integrating dual 16S rRNA amplicon reads

Kyoung Su Kim
Jihye Noh
Dong-Woo Lee
ResearchOpen Access12 Apr 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-14
Predicting Radiation Resistance in Breast Cancer with Expression Status of Phosphorylated S6K1

Jihye Choi
Yi Na Yoon
Min-Ki Seong
ResearchOpen Access20 Jan 2020
Scientific Reports

Volume: 10, P: 1-8

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SARS-CoV-2 spike-specific nasal-resident CD49a+CD8+ memory T cells exert immediate effector functions with enhanced IFN-γ production

Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

In vivo magnetogenetics for cell-type-specific targeting and modulation of brain circuits

FDA-approved phensuximide inhibits RIPK1-dependent immunogenic cell death

Refining microbiome diversity analysis by concatenating and integrating dual 16S rRNA amplicon reads

Predicting Radiation Resistance in Breast Cancer with Expression Status of Phosphorylated S6K1

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SARS-CoV-2 spike-specific nasal-resident CD49a⁺CD8⁺ memory T cells exert immediate effector functions with enhanced IFN-γ production