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Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision

Structural analysis of uracil DNA glycosylases in complex with DNA reveals that conserved H109 acts as a nucleophile to attack the oxocarbenium ion and makes a covalent bond to the abasic site after uracil excision to form a stable intermediate.

Woo-Chan Ahn
Shashanka Aroli
Eui-Jeon Woo
Research17 May 2019
Nature Chemical Biology

Volume: 15, P: 607-614
Coupling of radiofrequency with magnetic nanoparticles treatment as an alternative physical antibacterial strategy against multiple drug resistant bacteria

Akhilesh K. Chaurasia
Nanasaheb D. Thorat
Kyeong Kyu Kim
ResearchOpen Access27 Sept 2016
Scientific Reports

Volume: 6, P: 1-13

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Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision

Coupling of radiofrequency with magnetic nanoparticles treatment as an alternative physical antibacterial strategy against multiple drug resistant bacteria

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