The onset of septic cardiomyopathy (SC) is linked to excessive ROS, leading to increased oxidative stress and iron accumulation. Here, the authors report a conducting polymer-stabilized ruthenium nanozyme that shows desirable conductivity and catalytic properties, targets cardiac mitochondria, alleviates lipid peroxidation and oxidative stress, achieving precise therapeutic effects on SC.
- Tingting Wu
- Ying Liu
- Wei Jiang
