Nature Search

The E2F1-HMGCR axis promotes ferroptosis resistance in immune refractory tumor cells

HMGCR is upregulated by E2F1, driving ferroptosis resistance by reducing oxidative damage triggered by T cell-based therapy. Notably, targeting HMGCR restores ferroptosis sensitivity in immune-refractory tumors, enhancing response to PD-1 blockade as well as adoptive T cell transfer therapy.

Sung Wook Son
Hyo-Jung Lee
Kwon-Ho Song
ResearchOpen Access03 Dec 2025
Nature Communications

Volume: 16, P: 1-18
Fast and bright spontaneous emission of Er³⁺ ions in metallic nanocavity

The Purcell effect predicts a spontaneous emission rate enhancement of several orders of magnitude, but experimental demonstrations have been much lower. Here, Song et al. show emission enhancement of Er³⁺ions in a metallic nanocavity with a 170 Purcell factor at room temperature and 55% extraction efficiency.

Jung-Hwan Song
Jisu Kim
Yong-Hee Lee
ResearchOpen Access05 May 2015
Nature Communications

Volume: 6, P: 1-6
Polarization-sensitive in-sensor computing in chiral organic integrated 2D p-n heterostructures for mixed-multimodal image processing

In-sensor computing minimizes latency by directly processing data at the point of capture. Here, authors optimize this process by integrating polarization-sensitive detectors into the computing framework, enabling the superposition of two filtering operations within a single circuit.

Je-Jun Lee
Seong-Jun Han
Do Kyung Hwang
ResearchOpen Access19 May 2025
Nature Communications

Volume: 16, P: 1-11
Conductive-bridge interlayer contacts for two-dimensional optoelectronic devices

A gold-embedded oxide interlayer can be used to create metal–interlayer–semiconductor contacts for two-dimensional materials that exhibit low series resistance and Fermi level depinning.

Jisu Jang
Jung Pyo Hong
Do Kyung Hwang
Research05 Feb 2025
Nature Electronics

Volume: 8, P: 298-308
Highly efficient printed quantum dot light-emitting diodes through ultrahigh-definition double-layer transfer printing

Transfer printing of a quantum dot–ZnO film with a surface-functionalized viscoelastic stamp enables the realization of RGB QLED pixels with a resolution of 2,500 pixels per inch and a peak external quantum efficiency of 23.3% for green-emitting devices.

Jisu Yoo
Kyunghoon Lee
Moon Kee Choi
Research02 Aug 2024
Nature Photonics

Volume: 18, P: 1105-1112
Intrinsically stretchable quantum dot light-emitting diodes

Using an intrinsically stretchable nanocomposite of quantum dots, an elastomer and a hole transport polymer as an emissive layer, stretchable light-emitting diodes can be fabricated that exhibit high brightness even under 50% strain.

Dong Chan Kim
Hyojin Seung
Dae-Hyeong Kim
Research15 Apr 2024
Nature Electronics

Volume: 7, P: 365-374
Design of a UWB circularly-polarized planar monopole antenna using characteristic mode analysis

Hyuk Heo
Myeong-Jun Kang
Kyung-Young Jung
ResearchOpen Access31 Oct 2024
Scientific Reports

Volume: 14, P: 1-15
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Osteoarthritis is caused by the gradual accumulation of oxidative stress in cartilage. Here, the authors show that dysregulation of the selenium metabolic pathway underlies a shift in redox homeostasis in chondrocytes, leading to chronic osteoarthritic changes in joints.

Donghyun Kang
Jeeyeon Lee
Jin-Hong Kim
ResearchOpen Access09 Feb 2022
Nature Communications

Volume: 13, P: 1-14
Stable, Free-space Optical Trapping and Manipulation of Sub-micron Particles in an Integrated Microfluidic Chip

Jisu Kim
Jung H. Shin
ResearchOpen Access22 Sept 2016
Scientific Reports

Volume: 6, P: 1-9
Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia

Identifying the mechanisms underlying the early inflammatory phase of aortic valve disease is crucial for disease prevention. Here the authors perform single-cell RNA sequencing to show the immunomodulatory role of PPARγ in valvular endothelial cells during hyperlipidemia.

Seung Hyun Lee
Nayoung Kim
Jae-Hoon Choi
ResearchOpen Access17 Sept 2022
Nature Communications

Volume: 13, P: 1-22
Besifovir dipivoxil maleate versus other antivirals in reducing hepatocellular carcinoma in chronic hepatitis B

Jae Seung Lee
Sung Won Lee
Seung Up Kim
ResearchOpen Access29 Aug 2025
Scientific Reports

Volume: 15, P: 1-10
Deoxybouvardin targets EGFR, MET, and AKT signaling to suppress non-small cell lung cancer cells

A-Young Nam
Sang Hoon Joo
Jung-Hyun Shim
ResearchOpen Access06 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Therapeutic potential of histamine H₄ receptor antagonist as a preventive treatment for diabetic retinopathy in mice

Jung Won Kwon
Kihwang Lee
Seung Hyeok Seok
ResearchOpen Access30 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice

Hyesun Shin
Shinhee Park
Sung-Woo Park
ResearchOpen Access03 Jun 2023
Scientific Reports

Volume: 13, P: 1-15
Continuous Exposure to 1.7 GHz LTE Electromagnetic Fields Increases Intracellular Reactive Oxygen Species to Decrease Human Cell Proliferation and Induce Senescence

Jisu Choi
Kyeongrae Min
Kiwon Song
ResearchOpen Access08 Jun 2020
Scientific Reports

Volume: 10, P: 1-15
Metadynamics sampling in atomic environment space for collecting training data for machine learning potentials

Dongsun Yoo
Jisu Jung
Seungwu Han
ResearchOpen Access16 Aug 2021
npj Computational Materials

Volume: 7, P: 1-9
Unravelling the key factors for the dominance of Leuconostoc starters during kimchi fermentation

Jisu Lee
Min Ji Lee
Se Hee Lee
ResearchOpen Access25 Apr 2025
npj Science of Food

Volume: 9, P: 1-14
Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation

Jisu Park
Hyunwoo Choi
Yong-Keun Jung
ResearchOpen Access15 Jan 2021
Molecular Psychiatry

Volume: 26, P: 5542-5556
D-tyrosine adds an anti-melanogenic effect to cosmetic peptides

Jisu Park
Hyejung Jung
Eok-Soo Oh
ResearchOpen Access14 Jan 2020
Scientific Reports

Volume: 10, P: 1-11
iRhom1 regulates proteasome activity via PAC1/2 under ER stress

WonJae Lee
YoungDoo Kim
Yong-Keun Jung
ResearchOpen Access25 Jun 2015
Scientific Reports

Volume: 5, P: 1-14
Genetic variants in 3′-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans

Young Joo Jeon
Jong Woo Kim
Nam Keun Kim
ResearchOpen Access05 Jun 2015
Scientific Reports

Volume: 5, P: 1-12

Search

The E2F1-HMGCR axis promotes ferroptosis resistance in immune refractory tumor cells

Fast and bright spontaneous emission of Er³⁺ ions in metallic nanocavity

Polarization-sensitive in-sensor computing in chiral organic integrated 2D p-n heterostructures for mixed-multimodal image processing

Conductive-bridge interlayer contacts for two-dimensional optoelectronic devices

Highly efficient printed quantum dot light-emitting diodes through ultrahigh-definition double-layer transfer printing

Intrinsically stretchable quantum dot light-emitting diodes

Design of a UWB circularly-polarized planar monopole antenna using characteristic mode analysis

Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Stable, Free-space Optical Trapping and Manipulation of Sub-micron Particles in an Integrated Microfluidic Chip

Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia

Besifovir dipivoxil maleate versus other antivirals in reducing hepatocellular carcinoma in chronic hepatitis B

Deoxybouvardin targets EGFR, MET, and AKT signaling to suppress non-small cell lung cancer cells

Therapeutic potential of histamine H₄ receptor antagonist as a preventive treatment for diabetic retinopathy in mice

Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice

Continuous Exposure to 1.7 GHz LTE Electromagnetic Fields Increases Intracellular Reactive Oxygen Species to Decrease Human Cell Proliferation and Induce Senescence

Metadynamics sampling in atomic environment space for collecting training data for machine learning potentials

Unravelling the key factors for the dominance of Leuconostoc starters during kimchi fermentation

Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation

D-tyrosine adds an anti-melanogenic effect to cosmetic peptides

iRhom1 regulates proteasome activity via PAC1/2 under ER stress

Genetic variants in 3′-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans

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