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Advanced filters: Author: Joan Codina-Fabra Clear advanced filters

  • Nse2 is a SUMO E3 ligase component of the Smc5/6 multisubunit complex involved in the DNA repair and chromosome integrity. Here, the structure of the Nse2 in complex with an E2-SUMO thioester mimetic reveals the combined action of two SIM motifs during the E3- dependent conjugation reaction.

    • Nathalia Varejão
    • Jara Lascorz
    • David Reverter
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14