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Nature Cardiovascular Research (1)

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Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair

Wu et al. profile the secretome of cardiac endothelial cells exposed to endoplasmic reticulum (ER) stress during acute myocardial infarction and identify CRELD2 as an angiogenic growth factor supporting infarct repair.

Xuekun Wu
Linqun Zheng
Kai C. Wollert
ResearchOpen Access17 Jan 2024
Nature Cardiovascular Research

Volume: 3, P: 186-202

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Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair

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