Oxidative stress is known to play a role in lung cancer carcinogenesis with protein cysteines residues being key in redox signaling. Here, the authors discover in lung cancer patients through redox proteomics that there is a higher oxidation of the cysteines of glycolytic and methylglyoxal metabolism enzymes.
- Tamara Tomin
- Sophie Elisabeth Honeder
- Ruth Birner-Gruenberger